Gen info 
        Similax is a genus of about 300 to 500 species, found in temperate, tropics and subtropic zones worldwide. 
          Botany 
          Banag is a climbing woody vine reaching a height of several meters, occasionally to the canopy of trees it climbs.  Stems are armed with few to many stout spines. Leaves are elliptic to oblong-ovate, 8 to 13 centimeters long, the base broadly rounded or slightly cordate, and the apex shortly and abruptly acuminate. Umbels are many flowered, about 2 centimeters in diameter. Flowers are fragrant, greenish-yellow, and about 5 millimeters long. Berries are globose, 5 to 8 millimeters in diameter, black when mature. 
           Distribution 
          - In thickets and secondary forests at low and medium altitudes in Benguet, Pangasinan, Bulacan, Rizal, Bataan, Laguna and Quezon Provinces in Luzon. 
          Constituents 
            - Methanolic extract from rhizomes yielded six new phenolic compounds: (2S,3S)-5-O-β-d-glucopyranosyloxy-6-methyl-3‘-methoxy-3,7,3‘-trihydroxyflavan (1), (2S,3S)-5-O-β-d-glucopyranosyloxy-6-methyl-4‘-methoxy-3,7,4‘-trihydroxyflavan (2), 3β-(3‘,5‘-dihydroxyphenyl) 2α-(4‘‘-hydroxyphenyl)dihydrobenzofuran-5-carbaldehyde (3), (1-p-O-coumaroyl-6-O-feruroyl)-β-d-fructofuranosyl-α-d-glucopyranoside (4), (1-p-O-coumaroyl-3,6-di-O-feruroyl)-β-d-fructofuranosyl-α-d-glucopyranoside (5), and (6-O-feruroyl)-β-d-fructofuranosyl-(6-O-acetyl)-α-d-glucopyranoside (6).   (1) 
            - Ethanolic extract yielded six phenylpropanoid glycosides, smilasides G-L (1-6), along with four known phenylpropanoid compounds, helonioside A, heloioside B, smilaside E, and  (1-p-O-coumaroyl-6-O-feruroyl)-beta-d-fructofuranosyl-alpha-d-glucopyranoside, and 14 known phenolic compounds.  (see study above) (2)  
            - Rhizomes yielded five compounds: 5,7-dihydroxy-chromone-3-O-α-L-rhamnopyranoside (1), resveratrol (2), astilbin (3), neoisoastilbin (4), catechin (5).  (4) 
            and 
            - Study
            yielded major secondary metabolites: one aromatic compound seselin (1) and two steroids ß-sitosterol (2) and stigmasti-4-ene-3-one (3). (see study below)  (6) 
          Properties 
            - Depurative, emmenagogue. 
              - Studies have shown  radical scavenging activity.  
                 
                Parts used 
                  - Rhizomes, roots. 
                     
                    Uses  
                      Folkloric 
                        - In the Visayas, decoction of fresh or dry rhizomes used as emmenagogue. 
                          - Decoction of rhizomes and roots used as depurative. 
                            - Rhizomes used for rheumatism. 
                          - Decoction of roots or bark used by the Higanon tribe in Mindanao to relieve and prevent muscle pains or over fatigue in women, especially after childbirth. (5) 
                          - Mature stems used as herbal tooth sticks by inhabitants of the Andaman and Nicobar Islands. (7) Leaves used to treat urinary tract problems.  (8) 
                          - Root decoction used as diuretic and for various kidney troubles.   (9) 
                             
                            Studies  
                              • Phenolic Compounds: Study of methanol extract of Smilax bracteana rhizomes yielded six new phenolic compounds with five other known compounds. (see study above) (1) 
            • Antioxidant / Radical Scavenging Activity: Ethanolic extract yielded six phenylpropanoid glycosides, smilasides G-L along with four known phenylpropanoid compounds and 14 known phenolic compounds. Compounds 1-6 exhibited moderate scavenging activities against DPPH radicals. (see constituents above) (2) 
          • Aromatic and Steroid Compounds / Known Biologic Activities: Study isolated  major secondary metabolites: one aromatic compound seselin (1) and two steroids ß-sitosterol (2) and stigmasti-4-ene-3-one (3). These compounds have been shown to exhibit various biological activities such as anticancer, anti-fungal, and anti-inflammatory. (6) 
           Availability 
          Wild-crafted.  |