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Family Iridaceae
Iris domestica (L.) Goldblatt & Mabb.

Jiao jian cao

Scientific names  Common names
Belamcanda chinensis (L.) DC. Abaniko (Tag..) 
Belamcanda flabellata Grey Palma (Span, Tag.) 
Belamcanda pampaninii H.Lécv. Black berry lily (Engl.)
Bermudiana guttata Stokes Freckle face lily (Engl.)
Epidendrum domesticum L. Leopard flower (Engl.)
Ferraria crocea Salisb. Leopard lily (Engl.)
Gemmingia chinensis (L.) Kuntze  
Iris domestiica (L.) Goldblatt & Mabb.  
Ixia chinensis L.  
Ixia ensifolia Noronha  
Moraea chinensis (L.) Thunb.  
Moraea guttata (Stokes) Stokes  
Pardanthus chinensis (L.) Ker Gawl.  
Pardanthus nepalensis Sweet  
Pardanthus sinensis Van Houtte  
Vanilla domestica (L.) Druce  
Belamcanda chinensis (L.) DC. is a synonym of Iris domestica (L.) Goldblatt & Mabb. The Plant List
Iris domestica (L.) Goldblatt & Mabb. is an accepted name The Plant List

Other vernacular names
BENGALI: Dasba, Basbichandi.
CHINESE: Ye xuan hua, She gan, Jiao jian cao.
FRENCH: Fleur-leopard, Iris tigre
GERMAN: Leopardenblume, Pantherblume.
INDIA: Balamtandam, Valamcandam, Surajkaanti, Dasbaba
INDONESIA: Brojolintang, Suliga, Jamaka, Semprit, Wordi, Kiris, Katna
NEPAL: Tarbare.
SPANISH: Abanico, Palma.

Abaniko is an erect and tufted perennial rhizomatous herb with a thick creeping rootstock, growing to a height of 0.5 to 1.5 meters. Leaves are 2-ranked, strongly imbricated, narrow lanceolate, sword-shaped, 40 to 60 centimeters long, 2.5 to 4 centimeters wide, and overlapping at the base. Inflorescence is dichotomously branched, terminal and erect. Spathes are ovate to ovate-lanceolate, about 1 centimeter long. Flowers are numerous and pedicelled, opening 1 or 2 at a time, 4 to 6 centimeters across. Perianth-tube is very short, and the segments narrowly elliptic, spreading, yellowish outside, reddish-yellow inside with reddish spots. Capsules are obovoid, membranous and loculicidal. Seeds are nearly spherical in shape, with lax and shining testa.

- Planted for ornamental purposes, flowering most of the year.
- Nowhere naturalized.
- Native of southeastern Asia.
- Now cultivated in most warm countries.

- Rhizomes are bitter and acrid.
- Traditionally considered aperient, purgative, antipyretic, diuretic, expectorant, deobstruent, carminative and resolvent.

- Pulp considered stomachic.
- Studies have shown anticancer, antifungal, antioxidant, antidiabetic, hepatoprotective, antimutagenic, anti-inflammatory, antilipidemic, antibacterial, estrogenic properties..

- Study yielded two major isoflavonoid glucosides: iridin and tectoridin. (1)
- Study of ethanol extract of rhizomes yielded three compounds: isorhamnetin, hispidulin and dichotomitin. From the n-BuOH extract, iridin, tectoridin, daucosterol, vittadinoside or stigmasterol-3-O- glucoside. Four compounds were isolated from n-BuOH extracts: iridin, tectoridin, daucosterol, vittadinoside or stigmasterol-3-O-glucoside. (10)
- Ethyl acetate extract of roots isolated 18 compounds: (1), dausterol (2), quercetin (3), kaempferol (4), shikimic acid (5), gallic acid (6), ursolic acid (7), betulin (8), betulonic acid (9), betulone (10), tectoridin (11), irisflorentin (12), 4′,5,6-trihydroxy-7-methoxyisoflavone (13), tectorigenin (14), irilins A (15), iridin (16), irigenin (17), and iristectongenin A (18). (14)
- Dried rhizomes extracted with 80% ETOH and studied for isoflavones yielded 13 compounds, 10 of which were identified: tectoridin acetovanillone, 4-hydroxy-acetophenone, β-sitosterol, β-daucosterol, 5,7,4'-trihydroxyl-3',5'-di methoxyflavone, luteolin, apigenin ,5,7,4'-trihydroxyflavanones, isorharnnetin. (21)
- Ethanol extract of rhizomes yielded five compounds characterized as isoirigenin 7-O-β-D-glucoside (1), tectorigenin (2), irigenin (3), irilin D (4) and irisflorentin (5).

Parts utilized
Rhizomes, roots,

- Rhizomes used as expectorant.
- Used for purifying the blood, for liver and pulmonary complaints.
- In Malaya, used as a remedy for gonorrhea.
- In Malabar, used as alexipharmic.
- In Cochin-China (Vietnam), roots used for aperient and resolvent properties.
- Used as antidote to snakebites.
- In traditional Chinese medicine, used for pharyngitis, tonsillitis, cough, wheezing, bronchitis and mumps, blood purification, tumors of the face and breast. B. chinensis is an ingredient in the Chinese product--San Jin Xi Gua Xuang--used for sore throat, mouth and tongue ulcers.

Phenolic Content / Rhizomes / Anticancer: Three new compounds were identified– belalloside A, belalloside B and belamphenone along with other compounds resveratrol, iriflophenone, irisflorentine, tectoridin, among the 13 others. Results showed two isolates to have proliferation stimulatory activity against human breast cancer cell lines. (2)
Antifungal: A study on the antifungal activity of Belamcanda chinensis isolated a compound identical to tectorigenin (5,7-dihydroxy-3-(4-hydroxy phenyl)-6-methoxy-4H-1-benzopyran-4-one). This compound showed marked antifungal activity against dermatophytes of the genera Trichophyton. (3)
Phytoestrogens / Anticancer: Study demonstrated a role for tectorigenin and irigenin in regulating the number of prostate cancer cells by inhibition of proliferation through cell cycle regulation. (4)
Hepatoprotective / Antioxidative: Study of tectorigenin and tectoridin isolated from BC rhizomes was shown to have antioxidative and hepatoprotective activities in CCl4-intoxicated rats. (5)
Aldose Reductase Inhibition / Tectoridin / Antidiabetic: Aldose reductase is the key enzyme in the polyol pathway, and plays an important role in diabetic complications. Study isolated 12 phenolic compounds from the rhizomes of B. chinensis, with tectoridin and tectorigenin exhibiting the highest aldose reductase inhibitory potency. Administered in STZ-induced diabetic rats, it showed significant inhibition of sorbitol accumulation in the lens, RBC and sciatic nerves. (6)
Irigenin / Anti-Inflammatory: Study investigated the anti-inflammatory effects of six flavanoids isolated from the rhizomes of Belamcanda chinensis. Irigenin exhibited concentration-dependent inhibition of LPS-induced nitric oxide (NO) and prostaglandin (PGE2) production. (8)
Tectorigenin / Prostate Cancer: Study of showed who tectorigenin and other compounds extracted from B. chinensis can significantly rectify the aberrant expression of genes involved in prostate cancer. Irigenin from the rhizomes presents as a leading compound for anti-inflammation. (7)
Isoflavonoids / Antioxidant / Antimutagenic: Isoflavonoid fractions from a methanolic extract of BC rhizomes inhibited chemically induced mutations in S typhimurium TA98 and TA100 and also showed capability to scavenge free radicals. Results suggest additional value of the plant as a phytoestrogenic and chemopreventive agent. (9)
Phytoestrogens / Regulation of Steroid Receptors and Co-Factors in Prostate Cancer Cells: BCE showed beneficial effects on prostate cancer and rectifies the expression of key elements in hormone-refractory prostate cancer affecting tumor cell viability and proliferation. (13)
Antitumor Activities / Roots: Study of ethyl acetate extract of roots isolated 18 compounds.
Shikimic acid, betulin, betulonic acid and betulone showed potent cytotoxic activities against tumor cell lines. Compound 7 suggested a mechanisms of growth inhibition via induction of tumor cell apoptosis. (See constituents above) (14)
Hypoglycemic: Study of Bc leaf extract on normal and STZ-induced diabetic rats showed significant lowering of fasting blood glucose levels. Results suggest the isoflavone glycosides, not polysaccharides, to be the active fraction of BCL in diabetes treatment. (15)
Antitumor / Antioxidant: Various extracts of BC root were studied for in vitro antitumor activity against PC3, Bcap-37, and BGC-823 cell lines. Results showed an ethyl acetate extract and isolated fractions to have significant antitumor activity against the three cell lines. It also showed moderate DPPH free radical scavenging effects. (16)
α-Glucosidase Inhibiting Isoflavones / Leaves: Alpha-glucosidase inhibitors antagonize the activity of α-glucosidase, delaying absorption of carbohydrates and preventing the sharp increases in blood sugars after meals. Study evaluated the α-glucosidase inhibitory effect of BCL. Thirteen isoflavones were isolated. Six of the thirteen (swertisin, 2"-O-rhamnosylswertisin, genistein, genistin, mangiferin and daidzin) showed strong α-glucosidase inhibitory activity in vitro. Swertisin was the most abundant of the isoflavones and may be the principal component responsible for the α-glucosidase inhibition. (17)
Anti-Inflammatory / Inhibiting Isoflavones / Leaves: Study screened Formosan plants and Chinese herbs for anti-inflammatory activity. B. chinensis was found to be one of the active species. Study isolated two new isoflavone derivatives, 5-hydroxy-3′-methoxy-6,7:4′,5′-bis(methylenedioxy)isoflavone (1) and 5,7-dihydroxy-6,3′-dimethoxy-4′,5′-methylenedioxyisoflavone (2), along with 8 known compounds (3-10). Compound 9, isotectorigenin, exhibited potent inhibition of elastase release by human neutrophils in response to Met-Leu-Phe/Cytochalasin B. (18)
Tectorigenin Monohydrate / Isoflavone: Study isolated a tectorigenin monohydrate, an isoflavone, 5,7-dihydroxy-3-(4- hydroxyphenyl)-6-methoxy-4H-chromen-4-one monohydrate, which showed to have antimicrobiotic and anti-inflammatory effects. (19)
Tissue Specific Metabolites: Study showed the hydrophobic compounds, especially flavonoid or isoflavonoid aglycones and xanthone mainly accumulate in the cork, while the hydrophilic compounds, namely the flavonoid and isoflavonoid glycosides are usually found in the cortex or center. (20)
Anti-Hyperlipidemic / Leaves: Study evaluated the anti-hyperlipidemic effect of flavone-rich leaf extract of B. chinensis in mice fed a high fat diet. Results showed alleviation of hyperlipidemia, at least in part, by up-regulation mechanisms of AMPK and PPARα. (21)
Tectorigenin / Antibacterial / Anti-MRSA: Tectorigeninc (TTR) is an O-methylated isoflavone from the rhizome of B. chinensis. Study showed TTR has anti-MRSA (methicillin resistant Staphylococcus aureus) activity. TTR has a role in increasing cytoplasmic membrane permeability and decreasing activity of ABC transporter. Results suggest a potential for the use of TTR-based products in the treatment of MRSA. (22)
Phytoestrogens / Antiproliferative / Prostate Cancer Cells: Phytoestrogens are nonsteroidal plant derived compounds with estrogenic activity that have been implicated in protecting against prostate cancer progression. In vitro studies showed a role for tectorigenin and irigenin in regulating prostate cancer cell number by inhibiting proliferation through cell cycle regulation. (23)
Inhibitory Effects on Nitric Oxide Production: Study of methyl chloride fraction of rhizomes yielded 17 compounds. The isolated compounds were evaluated for inhibitory effects on nitric oxide production in LPS-induced RAW 264.7 macrophage cells. (24)
Analgesic / Anti-Inflammatory / Toxicity Evaluation / Tectorigenin: Tectorigenin is a main compound of B. chinensis. On subacute toxicity testing in mice, no toxic symptoms were observed at doses up to 300 mg/kg. It showed an analgesic effect on acetic acid-induced acute visceral pain in mice, and significant reduction of carrageenan-induced edema in an inflammatory rat model.  (25)
Tectorigenin / Anti-Proliferative / Malignant Testicular Germ Cell Tumors: Study demonstrated the potential of B. chinensis extract and tectorigenin as anticancer drugs in cell lines of malignant testicular germ cell tumor cells (TGCT) by inhibition of proliferation and regulating the expression of stem cell factors. The effects may be based on histone-dependent mechanisms such as direct hyperacetylation of transcription factors. (26)
Irisflorentin / Roots / Reduction of Allergic Contact Hypersensitivity Responses: Irisflorentin in an isoflavone component derived from the roots of B. chinensis. Study investigated the effects of irisflorentin on lipopolysaccharide (LPS)-stimulated maturation of mouse bone marrow-derived DCs (dendritic cells). Results showed irisflorentin can improved CHSR by blocking DC function.  (27)
In Vitro Estrogenic Activities: Study evaluated the estrogenic activities of 70% EtOH extracts of 32 traditional Chinese medicinal plants. Belamcanda chinensis, P. corylifolia and P. multiflorum showed a higher estrogenic relative inductive efficiency with RIE ranging from 83.7 to 52.1 (RIE of E2 was 100).  (28)
Anti-Osteoporotic Effects: Study evaluated the effect of medicinal herbs on osteoporosis, especially induced by estrogen deficiency, in an animal model. The B. chinensis extract containing tectorigenin had a strong hypothalamotropic and osteotropic effect without effects on the uterus or the mammary gland.  (29)
Anti-Trypanosomal Iridals: Study evaluated 196 extracts from traditional Chinese plants for potential to treat trypanosomal diseases. Bioassay guided fractionation of petroleum ether extract of Iris domestica led to the identification of several types of iridals with previously unreported anti-trypanosomal activity. (31) Bioassay-guided fractionation identified the myristate ester of iso-iridogermanal as an antitrypanosomal component of Iris domestica. The compound has ben shown to be cytotoxic to tumor cells.(34) Previously evaluated for activity against Trypanosoma brucei, bioassay-guided fractionation isolated four known iridals as active components. Chemical modification of the isolates afforded novel stable derivatives that maintained bioactivity. (35)
Tectorigenin / Prostate Cancer Therapy: Study demonstrated the potential of plant constituents, tectorigenin and irigenin, extracted from Belamcanda chinensis as therapies in prostate cancer. Results demonstrate B. chinensis markedly inhibited the development of tumors in vivo and suggests the compounds may be useful in the prevention and treatment of human prostate cancer. (32)
• Isoflorentin / Effect on
α-Synuclein Accumulation / Implications for Parkinson's Disease: PD is a degenerative disorder characterized by progressive loss of dopaminergic neurons in the substantia nigra pars compacta together with neuron impairment. Isoflorentin from the roots of Belamcanda chinensis was evaluated for its effect in amelioration of PD in Caenorhabditis elegans model. Results showed irisflorentin prevents α-synuclein accumulation in the CE model and improved dopaminergic neuron degeneration suggesting a potential as an anti-parkinsonian drug. It may exert effects by promotion of rpn-3 expression to block apoptosis pathways. (33)
• Neuroprotective / Iridal-Type Triterpenoids

- Cultivated.

- Seeds in the cybermarket.

Updated September 2018 / August 2017 / June 2015

IMAGE SOURCE: / Illlustration: :Iris domestica (as Ixia chinensis L.) / William Curtis / Plate 171 from The Botanical Magazine Vol 5, 1972 / Public Domain / Wikimedia
OTHER IMAGE SOURCE: / Flower close-up / dracobotanicus -- Wayne Dumbleton / Creative Commons Attribution / flickr / Click on graphic to see original image
OTHER IMAGE SOURCE: / Seeds / File:Belamcanda chinensis seeds.jpg / -- Doronenko / 16 September 2007 / GNU Free Documentation License / Attribution / Wikipedia / Click on graphic to see original image

Additional Sources and Suggested Readings
New flavone and isoflavone glycoside from Belamcanda chinensis
Chinese Chemical LettersVolume 18, Issue 2, February 2007, Pages 158-160
Phenolic constituents of rhizomes of the Thai medicinal plant with proliferative activity for two breast cancer lines / Monthakantirat,-O; De-Eknamkul,-W; Umehara,-K; Yoshinaga,-Y; Miyase,-T; Warashina,-T; Noguchi,-H
Detection of Antifungal Activity in Belamcanda chinensis by a Single-cell Bioassay Method and Isolation of Its Active Compound, Tectorigenin / OH Ki-Bong; KANG Heonjoong; MATSUOKA Hideaki /
Bioscience, Biotechnology, and Biochemistry, Volume 65, Issue 4, 2001 / DOI:10.1271/bbb.65.939
Antioxidant activities of isoflavones from the rhizomes of Belamcanda chinensis on carbon tetrachloride-induced hepatic injury in rats / Jung SHLee et al / Archives of Pharmacal Research / 2004V.27(no.2)
Isoflavonoids from the rhizomes of Belamcanda chinensis and their effects on aldose reductase and sorbitol accumulation in streptozotocin induced diabetic rat tissues
/ Sang Hoon Jung, Yeon Sil Lee et al / ARCHIVES OF PHARMACAL RESEARCH, Vol 25, Number 3, 306-312 / DOI: 10.1007/BF02976631
Tectorigenin and other phytochemicals extracted from leopard lily Belamcanda chinensis affect new and established targets for therapies in prostate cancer / Paul Thelen, Jens-Gerd Scharf et al / Carcinogenesis vol.26 no.8 pp.1360--1367, 2005 / doi:10.1093/carcin/bgi092
Inhibitory Effects Of Irigenin From The Rhizomes Of Belamcanda Chinensis On Nitric Oxide And Prostaglandin E(2) Production In Murine Macrophage RAW 264.7 Cells / hn KS, Noh EJ, Cha KH, Kim YS et al / Life Sci. 2006 Apr 11;78(20):2336-42. Epub 2005 Nov 2
Antimutagenic and antioxidant activities of isoflavonoids from Belamcanda chinensis (L.) DC / Dorota Wozniak, Bogdan Janda et al / Mutation Research/Genetic Toxicology and Environmental Mutagenesis
Volume 696, Issue 2, 2 February 2010, Pages 148-153 / doi:10.1016/j.mrgentox.2010.01.004
Study of chemical constituents of Belamcanda chinensis / Qin Min-Jan, Ji Wen-Ilang et al / Chinese Traditional and Herbal Drugs, 2004-05/
Belamcanda chinensis (L.) DC. / Catalogue of Life, China
Belamcanda chinensis / Vernacular names / GLOBin MED
Phytoestrogens from Belamcanda chinensis regulate the expression of steroid receptors and related cofactors in LNCaP prostate cancer cells / Paul Thelen, Thomas Peter, Anika Hünermund, Silke Kaulfu, Dana Seidlová-Wuttke†, Wolfgang Wuttke, Rolf-Hermann Ringert and Florian Seseke / JOURNAL COMPILATION © 2007 BJU INTERNATIONAL, 100, 199–203 / doi:10.1111/j.1464-410X.2007.06924.x
Chemical Constituents of the Ethyl Acetate Extract of Belamcanda chinensis (L.) DC Roots and Their Antitumor Activities / Mingchuan Liu, Shengjie Yang, Linhong Jin, Deyu Hu, Zhibing Wu and Song Yang */ Molecules 2012, 17, 6156-6169 / doi:10.3390/molecules17056156
Hypoglycemic effect of Belamcanda chinensis leaf extract in normal and STZ-induced diabetic rats and its potential active faction. / Phytomedicine : international journal of phytotherapy and phytopharmacology / DOI:
In vitro antitumor and antioxidant activities of Belamcanda chinensis (L.) DC / Mingchuan Liu, Shengjie Yang, Linhong Jin, Deyu Hu, Wei Xue, Song Yang* / Journal of Medicinal Plants Research, Vol. 6(43), pp. 5566-5569, 10 November, 2012 / DOI: 10.5897/JMPR11.1360
The α-Glucosidase Inhibiting Isoflavones Isolated from Belamcanda chinensis Leaf Extract
/ Chongming Wu1, Jingyao Shen, Pingping He, Yan Chen, Liang Li, Liang Zhang, Ye Li, Yujuan Fu, Rongji Dai, Weiwei Meng, *and Yulin Deng* / Rec. Nat. Prod. 6:2 (2012) 110-120
Anti-inflammatory natural products from Belamcanda chinensis / JJ Chen, ML Wu, TL Hwang, WJ Wu, YH Tsai, YJ Chen / Planta Med 2013; 79 - PI26 / DOI: 10.1055/s-0033-1352116
Tectorigenin monohydrate: an isoflavone from Belamcanda chinensis
/ Benguo Liu,* Yuxiang Ma, Han Gao and Qiong Wu / Acta Cryst. (2008). E64, o2056 / doi:10.1107/S1600536808030833
Tissue-specific metabolites profiling and quantitative analyses of flavonoids in the rhizome of Belamcanda chinensis by combining laser-microdissection with UHPLC-Q/TOF-MS and UHPLC-QqQ-MS / Chen YJ, Liang ZT, Zhu Y, Xie GY, Tian M, Zhao ZZ, Qin MJ / Talanta. 2014 Dec;130:585-97. / doi: 10.1016/j.talanta.2014.07.004. Epub 2014 Jul 9.
Studies on Bio-active Constituents of Belamcanda Chinensis and Eleutherine Americana / FengChuanWei / Master Thesis, 2010 / Second Military Medical University
The Antibacterial Assay of Tectorigenin with Detergents or ATPase Inhibitors against Methicillin-Resistant Staphylococcus aureus / Dae-Ki Joung, Su-Hyun Mun, Kuang-Shim Lee, Ok-Hwa Kang, Jang-Gi Choi, Sung-Bae Kim, Ryong Gong, Myong-Soo Chong, Youn-Chul Kim, Dong-Sung Lee, Dong-Won Shin, and Dong-Yeul Kwon / Evidence-Based Complementary and Alternative Medicine, Volume 2014 (2014) /
Chemical constituents from Belamcanda chinensis and their inhibitory effects on nitric oxide production in RAW 264.7 macrophage cells / Jin Woo Lee, Chul Lee, Qinghao Jin, Moon-Soon Lee, Youngsoo Kim, Jin Tae Hong, Mi Kyeong Lee, Bang Yeon Hwang / Archives of Pharmacal Research , Volume 38, Issue 6 , pp 991-997 / DOI: 10.1007/s12272-014-0529-8
Toxicity, analgesic and anti-inflammatory activities of tectorigenin
/ Le Minh Ha, Do Thi Nguyet Que, Do Thi Thanh Huyen, Pham Quoc Long, and Nguyen Tien Dat / Immunopharmacology and Immunotoxicology, June 2013, Vol. 35, No. 3 , Pages 336-340 (doi:10.3109/08923973.2013.770521)
Phytoestrogens regulate the proliferation and expression of stem cell factors in cell lines of malignant testicular germ cell tumors / Astrid Hasibeder Vivek Venkataramani Paul Thelen Heinz-Joachim Radzun / International Journal of Oncology, Volume 43, Issue 5, Nov 2013: Pages: 1385-1394 / DOI: 10.3892/ijo.2013.2060
Irisflorentin Modifies Properties of Mouse Bone Marrow-Derived Dendritic Cells and Reduces the Allergic Contact Hypersensitivity Responses / Ru-Huei Fu,* Chia-Wen Tsai, Rong-Tzong Tsai, Shih-Ping Liu, Tzu-Min Chan,** Yu-Chen Ho,* Hsin-Lien Lin,* Yue-Mi Chen,* Huey-Shan Hung, Shao-Chih Chiu,* Chang-Hai Tsai, Yu-Chi Wang, Woei-Cherng Shyu,* and Shinn-Zong Lin* / Cell Transplantation, Vol. 24, pp. 573–588, 2015 / DOI:
In vitro estrogenic activities of Chinese medicinal plants traditionally used for the management of menopausal symptoms / C.Z. Zhang, S.X. Wang, Y. Zhang, J.P. Chen, X.M. Liang / Journal of Ethnopharmacology 98 (2005) 295–300
Anti-osteoporotic Effects of Medicinal Herbs and their Mechanisms of Action / Yan Zhang, Mansau Wong, Chunfu Wu* / Asian Journal of Traditional Medicines, 2006, 1 ( 3-4 )
Iris domestica / Synonyms / The Plant List
Anti-Trypanosomal Iridals Isolated From Iris Domestica / A Liyana Pathiranage, J Moore Stubblefield, A Newsome, N Dunlap / Planta Med 2016; 82 - PC42 / DOI: 10.1055/s-0036-1578744
Studies on chemical constituents of Belamcanda chinensis / Ying-Kun Qiu, Y.-B. Gao, B.-X. Xu, K. Liu / Journal of Chinese Pharmaceutical Sciences 41(15):1133-1135 · August 2006
Irisflorentin improves α-synuclein accumulation and attenuates 6-OHDA-induced dopaminergic neuron degeneration, implication for Parkinson’s disease therapy / Yue-Mi Chen, Shih-Ping Liu, Hsin-Lien Lin, Ming-Chia Chan, Yen-Chuan Chen et al / Biomedicine (Taipei). 2015 Mar; 5(1): 4.  / doi: 10.7603/s40681-015-0004-y
Antitrypanosomal activity of an iridal from Iris domestica and initial structure-activity relationships / N Dunlap, AL Pathiranage, J Stubblefield, A Newsome / Planta Med 2015; 81 / DOI: 10.1055/s-0035-1556460
Antitrypanosomal activity of iridals from Iris domestica / Anuradha Liyana Pathiranage, Jeannie M Stubblefield, Xiaolei Zhou, Norma K Dunlap / Phytochemistry Letters, Dec 2016; 18: pp 44-50 / DOI:  10.1016/j.phytol.2016.08.025

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