Ayong-kabayo is a hairy vine reaching a height of at least 10 meters. Leaves are broadly ovate, 8 to 18 centimeters long, and 5 to 12 centimeters wide, with pointed tips, rounded or heart-shaped bases and toothed margins. Flowers are greenish with a purple tinge, subumbellately arranged on the ultimate branchlets on cymes 2.5 to 5 centimeters long. Fruit is fleshy, purple when mature, rounded and about 1 centimeter in diameter, containing a single, large, pear-shaped, smooth seed.
- In thickets at low and medium altitudes, from northern Luzon to Mindanao.
- Also reported in India to Indo-China and southward to Timor.
- Considered alterative and diuretic.
Roots and tubers.
- Not known medicinally in the Philippines.
- In India, the decoction of dried tubers used as alterative and as diuretic.
- Extracts have been used for dissolution and expulsion of urinary stones.
- Root, powdered and heated, applied to cuts and fractures by the Santals.
- In Bangladesh, plant traditionally used for treatment of boils, bruises, epilepsy, fever, food poisoning, gastric tumors, jaundice, gout, hysteria, snake bites, urolithiasis, etc.
- In Kerala, India, decoction of tuber considered diuretic, alterative, and blood purifying.
• Antibacterial / Anti-Urolithiasis: Study of 17 plant species screened for potential antibacterial activity against four selected urolithiasis-inducing flora (P mirabilis, E coli, Pseudomonas stutzeri and K pneumonia) showed six plants, including C. adnata to show promising roles in the prevention and cure of urolithiasis. (1)
• Free Radical Scavenging Activity: Study yielded a triterpenoid, flavonoid and apigenin. Study comparing isolated compounds of C. adnata and Smilax lanceaefolia showed the compounds to have moderate to high free radical scavenging activities. (3)
• Chemoinhibitory Effect / Antiurolithiatic: Studies on Cissus adnata have suggest antilithiatic property. An aqueous extract of leaves and isolated compounds showed an inhibitory effect on the formation of calcium phosphate and calcium oxalate stones in the urinary millieu. There was greater inhibitory effect on calcium oxalate formation than calcium phosphate crystal formation. (6)
• Antibacterial Efficacy on Urolithiasis Inducing Flora: In a study evaluating plants as sources of novel antibacterials associated with prevention and control of urolithiasis, Cissus adnata was one of the plants that exhibited significant antibacterial activity against four selected urolithiasis inducing flora (P. mirabilis, E. coli, Pseudomonas stutzeri, and K. pneumonia subsp. pneumonia), showing promising role in the prevention and cure of urolithiasis. (7)