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Family Lamiaceae
Orthosiphon aristatus (Blume) Miq.

Mao xu cao

Scientific names  Common names 
Clerodendrathus spicatus (Thunb.) C.Y.Wu Balbas-pusa (Tag.) 
Clerodendrathus stamineus (Benth.) Kudo Kabling-gubat (Tag.) 
Clerodendrum spicatum Thunb. Kabling-parang (Tag.) 
Ocimum aristatum Blume Cat's whiskers (Engl.)
Ocimum grandiflorum Blume [Illegitimate] Indian kidney tea (Engl.)
Orthosiphon aristatus (Blume) Miq. Java tea (Engl.)
Orthosiphon spiralis (Lour) Merr. Kidney tea plant (Engl.)
Orthosiphon stamineus Benth.  
Orthosiphon tagawae Murata  
Trichostema spirale Lour.  
Kabling-parang is a shared common name of two medicinal plants: (1) Anisomeles indica, Malabar catmint, kabling lalake, and (2) Orthosiphon aristatus, Kabling-gubat, Balbas-pusa, Cat's whisker
Cat's whisker is a common name shared by: (1) Orthosiphon aristatus, Kabling-gubat, Balbas-pusa, and (2) Gynandropsis gynandra, spider flower.
Orthosiphon aristatus (Blume) Miq. is an accepted name. The Plant List

Other vernacular names
CAMBODIAN: Kapen prey.
CHINESE: Mao xu cao.
FRENCH: Java thé, Moustaches de chat.
GERMAN: Katzenbart.
INDONESIAN: Kutum, Mamam, Bunga laba-laba, Kumis ucing, Remuk jung, Songot koceng, Sesalaseyan.
JAPANESE: Nek no hige.
MALAYSIAN: MIsai kucing, Ruku hutan.
MYANMAR: Se-cho, Myit-shwe.
THAI: Yaa-nuat-maeo, Yaa-nuad-maew, Pa-yab-mek.

Kabling-gubat is a slender, smooth or hairy undershrub, 30 to 60 centimeters high. Leaves in distant pairs, narrowed into the stalk, ovate, 5 to 10 centimeters long, pointed at both ends, coarsely toothed at the margins. Flowers are borne in very lax racemes. Calyx is bell-shaped, with a naked throat and two slender lower teeth. Corolla is 2.5 centimeters long, smooth, white or purplish, very slender in the tube, and thrice as long as the calyx. Nutlets are oblong and compressed.

- In thickets, at low and medium altitudes in Cagayan, Isabela, Nueva Ecija, Pampanga, Bulacan, and Rizal Provinces in Luzon; and in Coron.
- Also occurs in India through Malaya to tropical parts of Australia.

- Leaves contain a high percentage of potassium salts (0.738 gm in 100 grams of fresh leaves.
- From dried leaves, a small amount of volatile oil and a bitter alkaloid, orthosiphonin.
- Studies yielded flavonoids, carbohydrates, tannins, saponins, phenols, and terpenoids.
- Phytochemical screening yielded twenty compounds: nine lipophilic flavones, two flavonol glycosides, and nine caffeic acid derivatives. Caffeic acid derivatives included the major compounds rosmarinic acid and 2,3-dicaffeoyltartaric acid.
- Major constituents are sesquiterpenes including ß-elemene, ß-caryophyllene, orthochromene A, acetovanillochromene, sinensetin, tetramethyl scutellarein, eupatorin, neoorthosiphons A and B. (25)
- Study of methanolic extract of aerial parts yielded
five new isopimarane-type diterpenes [orthosiphols F-J (1-5)] and two new diterpenes [staminols A (6) and B (7)] and three new highly-oxygenated staminane-type diterpenes [staminolactones A (8) and B (9) and norstaminol A (10)] along with 16 known compounds, 7,3􏰍,4􏰍-tri-O-methylluteolin (11), eupatorin (12), sinensetin (13), 5-hydroxy-6,7,3􏰍,4􏰍-tetra- methoxyflavone (14), salvigenin (15), ladanein (16), tetramethylscutellarein (17), 6-hydroxy-5,7,4􏰍-trimethoxy- flavone (18), vomifoliol (19), aurantiamide acetate (20), rosmarinic acid (21), caffeic acid (22), oleanolic acid (23), ursolic acid (24), betulinic acid (25), and b-sitosterol (26). (see study below) (39)

- Considered anti-allergic, anti-inflammatory, anti-bacterial, diuretic and hypoglycemic.
- Studies have showed diuretic, antioxidant, anti-tumor, hypouricemic, nephroprotective, anti-diabetic, antihypertensive, anti-inflammatory, antimicrobial, hepatoprotective, antifungal, properties.

Parts utilized

- Tea made from leaves and fresh or dried flowers.
- Leaves are bitter with a characteristic odor.
- Leaves reportedly rich in potassium (738 mg/ 100 g of fresh leaves).


- Leaves used for gout and renal disorders.
- Also used for its diuretic effect.
- Poultice of leaves or chewed leaves stuffed onto painful tooth.
- In South East Asia and Australia, frequently used for renal inflammation, kidney stones and dysuria.
- In Holland and France, reported use for treatment of genitourinary diseases.
- In Malaysia, traditionally used for bladder catarrh, diabetes, kidney diseases, for hypertension and as diuretic.
- In Java, leaves made into tea for treatment of diseases of the kidney and bladder. Used as diuretic and for treatment of diabetes, rheumatism, hypertension, and biliary lithiasis. In Malaysia, used for treatment of catarrh; plant decoction used to eliminate bladder stones. In Japan, used a tea to facilitate body detoxification. (24)
- Java Tea is derived from Orthosiphon aristatus, touted for its diuretic action, kidney flushing benefits for kidney and bladder stones.
- New age uses: Extracts used for skin whitening and as anti-cellulitic. Creams and lotions used to decrease skin oiliness.

Antihypertensive / Methylripariochromene A: Methylripariochromene A (MRC), isolated from the leaves of OA showed blood pressure lowering effect and a vasodilating action, decrease cardiac output and diuretic action. It supports the traditional use of the plant for hypertension treatment. (1)

Na+,K+-ATPase Inhibition: In the study of ten Thai indigenous medicinal plants, O aristatus showed high potent inhibitory activity. (2)
Inhibition of Smooth Muscle Contraction: Three Indonesian medicinal plants were studied for their biologically active constituents. Three benzochromenes and four isopimarane-type diterpenes isolated from the leaves of Orthoshiphon aristatus were shown to exhibit inhibitory effects on smooth muscle contractions caused by several stimulants (3)
Pimarane-type Diterpenes / Suppressive Effect on Thoracic Aortic Contraction: Study isolated pimarane-type diterpenes, neoorthosiphols A and B, and other known compounds from the water decoction of leaves of O. aristatus. The compounds exhibited a suppressive effect on contractile responses in rat thoracic aorta. (10)
Diuretic: O. stamineus extract exhibited dose-dependent diuretic activity with a significantly increased excretion of K. There was also slight increase of BUN, creatinine and blood glucose levels, although statistically significant when compared to control , the levels were considered within normal range. Although less potent than furosemide and HCTZ, care should be taken in its consumption because of alterations in kidney parameters.
Nephrolitihiasis Study : In a randomized control trial of Orthosiphon versus placebo, no statistically significant difference was found. (6)
Hepatoprotective : A study on the methanol extract of leaves of Orthosiphon stamineus against paracetamol-induced hepatotoxicity showed treatment with OS extract brought back the altered biochemical markers in a dose-dependent manner suggesting hepatoprotective activity. (2) Study showed dose-dependent in vivo hepatoprotective activity of Et-F on liver injury induced by CCl4 in mice. (8) Study showed the hepatoprotective effect of Orthosiphon stamineus which was attributed to antioxidant and free radical scavenging properties. (28)
Diuretic / Hypouricemic : A study on the methanol extract of OS showed significantly increased excretion of sodium and potassium excretion in a pattern comparable to hydrochlorothiazide. It also showed reduced serum urate level in hyperuricemic rats. Study provides evidence towards a diuretic and hypouricemic effect in rats. (9)
Antioxidant / Anti-Inflammatory : A study results showed the ethanolic extract and its bioactive compound, ursolic acid, suppress LPS-induced NO and PGE2 production by inhibiting ROS generation, along with reducing expression of iNOS and COX-2 in RAW 264.7 cells. (11)
Radical Scavenging Activity / Flavonoid : Study concludes a correlation between flavonoid content and radical scavenging activity. In the study, F obovata, D lobbiana and O aristatus exhibited the highest free radical scavenging activity. (12)
No Diuretic Effect / Double-Blind Placebo-Controlled Study: In a study of four traditional Vietnamese herbal remedies (Z mays, I cylindrica, Plantago major, O stamineus) claiming to increase diuresis, no diuretic effect was seen in a placebo-controlled double-blind crossover model.
Antioxidant / Hepatoprotective : Study showed dose-dependent in vivo hepatoprotective activity of Et-F on liver injury induced by CCl4 in mice. An n-butanol fraction showed higher in vitro antioxidant activity on FRAP assay than others in the DPPH assay. Results show O. aristatus is a potential source of natural antioxidants and hepatoprotective agents. (15)
Nephroprotective: Study in rats investigated the nephroprotective effect of O. stamineus in gentamicin-induced renal damage. Lab parameters were improved and the extent of renal damage was decreased by a methanolic extract of O. stamineus. (16)
Histamine Antagonist / Anti-Asthma: Study showed OA exhibited bronchodilator and antihistamine action as theophylline did. Results propose several mechanisms of actions: (1) chemical constituents that might stimulate adenyl cyclase that stimulates increase cAMP production from ATP, with consequent vasodilatation and bronchodilation. (2) extract may inhibit phosphodiesterase with consequent increase in cAMP (3) extract could be a histamine antagonist, or (4) anticholinergic activity. (19)
Anti-Inflammatory / Leaves: Study of leaf extracts showed anti-inflammatory activity. The flavonoid rich chloroform extract fraction containing sinensetin, eupatorin, and 3'-hydroxy-5,6,7,4'-tetramethoxyflavone, significantly reduced rat hind paw edema, NO, and decreased dye leakage. Results suggest the anti-inflammatory effects may be due to the presence of flavonoid compounds affecting the NO pathway.   (18)
Anthelmintic: Study evaluated the efficacy of O. aristatus aqueous crude extract as anthelmintic. Results showed effective control of swine parasites with decreased number of worm eggs and reduced number of adult worms. (20)
• Antihypertensive: Study investigated the effect of oral O. stamineus on the blood pressure of spontaneously hypertensive rats. A two-week administration showed significant mean reduction of blood pressure among SHR. (21)
Antioxidant / Toxicity Study: Study evaluated the antioxidant activity and potential toxicity of a 50% methanolic extract of leaves after acute (5000 mg/kg single dose) and subchronic (1250, 2500, and 5000 mg/kg/day for 28 days) administration in rats. Results showed good superoxide radical scavenging, hydroxyl radical scavenging, ferrous ion chelating, and antilipid peroxidation activities. No mortality or any signs of toxicity was detected in the acute and subchronic toxicity studies. The oral lethal dose was more than 5000 mg/kg with NOAEL and MEOS for both male and female rats of 5000 mg/kbw per day. (22)
• Antiobesity: Administration of O. stamineus extract for two weeks significantly decreased total food intake, weight gain and visceral fat deposition in rats Decrease food intake was associated with an increase of hypothalamic POMC expression while decreasing NPY expression was caused by elevation of plasma leptin level. (24)
• Drug Interactions / Lithium: (Moderate interaction) Lithium interacts with Java tea. Java tea might decrease the excretion of lithium and increase its blood level which may require an adjustment of its dose. (26) Patients should also be cautioned that the herb can augment the prescription diuretic effects.
• Nephroprotective / Ethylene Glycol Induced Urolithiasis / Leaves: Study of ethanolic extract of leaves of O. stamineus showed nephroprotective activity in ethylene glycol induced urolithiasis in albino rats. Results showed an effective decrease in the abnormal level of biomarkers involved in the kidney defect. (27)
• Potentiation of Herb-Drug Interaction / Interaction with Human Cytochrome P450: Extract showed moderate inhibition towards CYP2C9 with IC50 of 49.90, 89.24, and 97.82 µg/mL for CYP1A2, CYP2D6, and CYP3A4, respectively. Results suggest O. stamineus extract may potentiate herb-drug interaction via CYP inhibition. (29)
• Anti-Diabetic / α-Glucosidase Inhibitors / Leaves: Study of an aqueous extract of leaves isolated methyl caffeate (1), 3,4-dihydroxy benzaldehyde (2), methyl rosmarinate (3) and rosmarinic acid (4). These compounds were active against α-glucosidase from the rat intestine (maltase and sucrase) with IC50 values in the range of 0.061-0.738 mM, equipotent to standard antidiabetic drug acarbose. (30)
• Effect of Storage / Leaves and Stems: Study evaluated the effect of different storage durations on the phytochemical profile of O. aristatus leaves and stems examining total phenolics and flavonoid contents, antioxidant capacities. The leaf extract was likely to have more phytochemicals than stem extract, particularly caffeic acid derivatives including glycosylated and alkylated caffeic acids. There was higher ration of total phenolics to total flavonoid content with higher antioxidant capacities for the leaf extracts. Rosmarinic acid dimer and salvianolic acid B were major constituents. The phytochemical profile was at least stable for a month stored at 4ºC. As herbal tea, it has comparable radical scavenging activity as other tea samples, although lower in caffeine content. (31)
• Antibacterial / Leaf and Leaf Callus: Study evaluated the antibacterial efficacy of various extracts of leaf and leaf derived callus against B. cereus, B. subtilis, S. aureus, S. pyogenes, E. aerogenes, E. coli, P. mirabilis, and K. pneumonia. An ethanolic leaf extract showed maximum inhibitory activity with 28 mm zone of inhibition against P. mirabilis with MIC of 0.32 mg/ml. The ethanolic callus extract showed maximum bioefficacy against S. aureus with 26 mm ZOI and MIC of 0.64 mg/ml. Bioefficacy study confirmed strong antibacterial potential of leaf and leaf derived callus of O. aristatus. (32)
• Cognition Enhancer / Invention: Invention related to the use of compounds of isopimarane diterpene type, e.g. obtainable from extracts of Orthosiphon species, for use in the management of cognitive performance. (33)
• Antidiabetic: Previous study has shown that the sub-fraction of a chloroform extract was able to inhibit the rise of blood glucose levels in a GTT. This study evaluated the chronic effect and possible mechanism of action of a bioactive chloroform sub-fraction of O. stamineus using in vitro methods and STZ-induced diabetic rats. Results showed significant reduction of glucose absorption in everted rat jejunum. There was no evidence of effect on insulin release. Results suggest an extra-pancreatic mechanism. (34)
• Cytotoxicity / Leaves and Flowers: Study evaluated the cytotoxicity and phytochemical content of O. stamineus leaves and flowers solvent extracts. Cytotoxicity evaluation by MTT assay towards Vero cell showed CC50 values between 3.4-7.4 mg/ml, and can be considered nontoxic. Phytochemical screening yielded terpenes, alkaloids, and phenolics. (35)
• Flavonoids Eupatorin and Sinensetin / Anti-Inflammatory / Leaves: Study evaluated the anti-inflammatory properties of Orthosiphon stamineus leaf chloroform extract, CF2 fraction, flavonoids eupatorin and sinensetin. Results showed the chloroform extract and CF2 fraction inhibited iNOS expression, NO production, and PGE2 production. Eupatorin and sinensetin inhibited iNOS and COX-2 expression and production of NO and PGE2. The extracts and compounds also inhibited tumor necrosis factor a (TNFa) production. Eupatorin and sinensetin also inhibited LPS-induced activation of transcription factor signal inducers and also inhibited carrageenan-induced paw inflammation in mice. Results suggest potential for use in the development of novel anti-inflammatory treatments. (36)
• Protective Mechanisms in Diabetes Using Urine Metabolomics: Study evaluated the metabolic protective mechanism of O. stamineus in diabetes mellitus using STZ-induced experimental model in rats. Results showed reversal of metabolic abnormalities comparable to that of glibenclamide. A systematic metabolic pathways analysis showed the aqueous extract contributed to antidiabetic activity mainly through regulation of tricarboxylic acid cycle, glycolysis/gluconeogenesis, lipid and amino acid metabolism. (37)
• Antifungal to Candida albicans / Leaves: Study evaluated the antifungal potential of Orthosiphon aristatus leaf extract against growth of Candida albicans. While ketoconazole showed greater inhibition of C. albicans, Orthosiphon aristatus leaf extract showed inhibition of C. albicans growth with most optimal inhibitory concentration of 25%. Results suggest a potential as alternative natural anticandidiasis drug. (38)
• Cytotoxicity Towards Highly Liver Metastatic Murine Colon Carcinoma Cells: Study of methanol extract of aerial parts of Orthosiphon stamineus yielded five new isopimarane-type diterpenes (orthosiphols F-J [1-5]), two diterpenes (staminols A and B [6,7]), three new highly oxygenated staminane-type diterpenes (staminolactones A and B and norstaminol A [8,9,10]), along with 16 known compounds. All isolated diterpenes, except for 4, and flavonoids 11, 12, 16, and 18 showed weak cytotoxicity against highly liver metastatic murine colon 26-L5 carcinoma cells, with ED50 between 50 and 90 µg/ml. (see constituents above) (39)

Toxicity Study
Chronic Toxicity Test: A study on the chronic toxicity of water extract of Orthosiphon aristatus on Wistar rats showed that high doses of the extract caused a reduction of serum sodium levels in all extract-treated groups and increase alkaline phosphatase level and incidence of hydrocalyx in male rats, therefore advising that the prolonged use of OA should be avoided. (7)

Tea, powders, extracts in the cybermarket.

Updated February 2019 / April 2017 / March 2014

Photos / Content © Godofredo Stuart / StuartXchange

Additional Sources and Suggested Readings
Antihypertensive actions of methylripariochromene A from Orthosiphon aristatus, an indonesian traditional medicinal plant / Matsubara T, T Bohgaki, M Watarai, H Suzuki, K Ohashi, H Shibuya / Biological & Pharmaceutical Bulletin / Oct 1999; 22(10): pp 1083-1088 / DOI10.1248/bpb.22.1083 / PMID: 10549860
Inhibitory effects of selected Thai medicinal plants on Na+,K+-ATPase / Nattaya Ngamrojanavanich et al / Fitoterapia, Vol 77, Issue 6, September 2006, Pages 481-483 / doi:10.1016/j.fitote.2006.06.003 |
Three Indonesian medicinal plants were studied for their biologically active constituents /
Diuretic properties of Orthosiphon stamineus Benth / Y. Adam, M.N. Somchit et al / Journal of Ethnopharmacology Vol 124, Issue 1, 6 July 2009, Pages 154-158 / doi:10.1016/j.jep.2009.04.014 /

Chemical Specification of Orthosiphon aristatus (Blume) Miq. / Duangpen Pattamodilok et al / Medicinal Plant Research Institute, Department of Medical Sciences, Nonthaburi 11000, Thailand.
Orthosiphon Versus Placebo in Nephrolithiasis with Multiple Chronic Complaints: A Randomized Control Trial / Amorn Premgamone et al / eCAM 2009 6(4):495-501; doi:10.1093/ecam/nem141
Chronic toxicity test of Orthosiphon aristatus (Bl.) miq.extract / Bulletin of Department of Medical Sciences 1999; 41(1): 41-54 / Medicinal Plant Research Institute, Department of Medical Sciences / Division of Clinical Pathology, Department of Medical Sciences, Tiwanond Road, Nonthaburi11000
Hepatoprotective Activity of “Orthosiphon stamineus” on Liver Damage Caused by Paracetamol in Rats
/ C. Maheswari, R.Maryammal and R. Venkatanarayanan / Jordan Journal of Biological Sciences, Vol 1, Number 3, Pages 105 -108, September. 2008
Studies on diuretic and hypouricemic effects of Orthosiphon stamineus methanol extracts in rats / O.M. Arafat, S.Y. Tham et al / Journal of Ethnopharmacology / Volume 118, Issue 3, 13 August 2008, Pages 354-360/ doi:10.1016/j.jep.2008.04.015

Indonesian Medicinal Plants. XXIII.1) Chemical Structures of Two New Migrated Pimarane-type Diterpenes, Neoorthosiphols A and B, and Suppressive Effects on Rat Thoracic Aorta of Chemical Constituents Isolated from the Leaves of Orthosiphon aristatus (Lamiaceae) / Kazuyoshi Ohashi et al / Chem. Pharm. Bull. 48(3) 433—435 (2000)
Antioxidant and Anti-Inflammatory Effects of Orthosiphon aristatus and Its Bioactive Compounds / Chin-Lin Hsu et al / J. Agric. Food Chem., 2010; 58(4): pp 2150–2156 / DOI: 10.1021/jf903557c
Free Radical Scavenging Activity of Some Malaysian Medicinal Plants / Muhammad Taher / 19th CPA-MPS 2007, KUALA LUMPUR
Studies on the individual and combined diuretic effects of four Vietnamese traditional herbal remedies (Zea mays, Imperata cylindrica, Plantago major and Orthosiphon stamineus) / Doan Du Dat, Nguyen Ngoc Ham et al / Journal of Ethnopharmacology, Volume 36, Issue 3, June 1992, Pages 225-231 / doi:10.1016/0378-8741(92)90048-V
Qualitative and Quantitative Analysis of the Phenolic Constituents from Orthosiphon aristatus.
/ Sumaryono W, Proksch P, Wray V, Witte L, Hartmann T. / Planta Med. 1991 Apr;57(2):176-80.
Antioxidant and Hepatoprotective Effects of Orthosiphon aristatus on Liver Damage Induced by CCl4 in Mice / Natural Institute of Medicinal Materials (NIMM)
Efficacy of Orthosiphon aristatus and Norfloxacin in theTreatment of Patients with Multiple Chronic Health Complaints under Restriction of Purine-rich Food / Amorn Premgamone, Pote Sriboolue, Srinoi Maskasem, Wattana Ditsataporncharoen / Journal of Thai Traditional and Alternative Medicine
HPLC and Anti-Inflammatory Studies of the Flavonoid Rich Chloroform Extract Fraction of Orthosiphon Stamineus Leaves / Mun Fei Yam, Vuanghao Lim 1, Ibrahim Muhammad Salman et al / Molecules 2010, 15, 4452-4466; doi:10.3390/molecules15064452
Effect of Orthospihon aristatus Extract as Histamine Antagonist on Tracheal Chain of Guinea Pig / Nantaya Chanarat et al / Bull Chiang Mai Assoc Med Sci, Vol 30, Suppl No 1, 1997
The Anthelmintic Property of Orthosiphon aristatus (Balbas Pusa) Ethanolic Extract / JHOANNA B. CALUBAQUIB / doi: http://dx.doi.org/10.7718/iamure.ijscl.v4i1.630 / International Peer Reviewed Journal, Vol. 4 June 2013
The antihypertensive effect of Orthosiphon stamineus extracts: A preliminary study on Spontaneous Hypertensive Rats  / Nurul Alia Azizan, Rashidi Ahmad, Zaini Asmawi / Paperback, July 17, 2011
Antioxidant and Toxicity Studies of 50% Methanolic Extract of Orthosiphon stamineus Benth / Mun Fei Yam, Chung Pin Lim, Lee Fung Ang, Lip Yee Por, Siew Tung Wong, Mohd. Zaini Asmawi, Rusliza Basir, and Mariam Ahmad / BioMed Research International, Volume 2013 (2013) / http://dx.doi.org/10.1155/2013/351602
Orthosiphon aristatus / Synonyms / The Plant List
A Review of the Medicinal Plants of Genus Orthosiphon (Lamiaceae) / Mukesh K. Singh, Bina Gidwani, Anshita Gupta, Hemant Dhongade, Chanchal Deep Kaur, Pranita P. Kashyap and D.K. Tripathi / International Journal of Biological Chemistry 9 (6): 318-331, 2015 ISSN 1819-155X / DOI: 10.3923/ijbc.2015.318.331
Java Tea Interactions / WebMD
Nephroprotective activity of Ethanolic Extract of Orthosiphon stamineus Leaves on Ethylene Glycol induced Urolithiasis in Albino Rats / K. Ramesh, S Manohar and S. Rajeshkumar* / International Journal of PharmTech Research, Vol.6, No.1, pp 403-408, Jan-March 2014
Antioxidant and Hepatoprotective Effects of Orthosiphon stamineus Benth / Mun Fei Yam et al / Am. J. Chin. Med., 2007;  35(1): pp 115-126 /  DOI: http://dx.doi.org/10.1142/S0192415X07004679
Internaction Study: The Effect of Orthosiphon stamineus Extract of Human Cytochrome P450 / Purwantiningsih, Abas Hj Hussin / Indonesian Journal of Pharmacy, Vol 25, No 4, 2015
α-GLUCOSIDASE INHIBITORS FROM JAVA TEA Orthosiphon aristatus (Blume) Miq. / Doungkamon Toumsuk, Preecha Phuwapraisirisan* / IBSC
Phytochemical profile of Orthosiphon aristatus extracts after storage: Rosmarinic acid and other caffeic acid derivatives. / Chua L S, Lau C H, Chew C Y, Ismail N I M, Soontorngun N / Phytomedicine, Jan 2018; 15(39): pp 49-55 / j.phymed.2017.12.015. Epub 2017 Dec 18. / doi: 10.1016/j.phymed.2017.12.015
EVALUATION OF ANTIBACTERIAL POTENTIAL OF LEAF AND LEAF DERIVED CALLUS EXTRACTS OF ORTHOSIPHON ARISTATUS (BLUME) MIQ. / Nissar Ahmad Reshi, Sudarshana Mysore Shankarsingh, Girish Vasanaika Hodiyala / Pharmaceutical and Clinical Research, May 2017; 10(5) / DOI  https://doi.org/10.22159/ajpcr.2017.v10i5.17231
Orthosiphon stamineus extracts with beneficial use as cognition enhancer  / WO2011078652A1 / WIPO (PCT)
Antidiabetic Properties and Mechanism of Action of Orthosiphon stamineus Benth Bioactive Sub-fraction in Streptozotocin-induced Diabetic Rats / Elsnoussi Ali Hussin Mohamed, Mun Fei Yam, Lee Fung Ang, Ali Jimale Mohamed, Mohd Zaini Asmawi / Journal of Acupuncture and Meridian Studies, 2013; 6(1): pp 31-40 / http://dx.doi.org/10.1016/j.jams.2013.01.005
Cytotoxicity and phytochemical analyses of Orthosiphon stamineus leaves and flower extracts / Alaa Abd Alwahid, Wan Mohtar Wan Yusoff, Norefrina Shafinaz Md. Nor, and Nazlina Ibrahim / AIP Conference Proceedings, 2015; 1678, 030010 /  https://doi.org/10.1063/1.4931231
Flavonoids Eupatorin and Sinensetin Present in Orthosiphon stamineus Leaves Inhibit Inflammatory Gene Expression and STAT1 Activation / Mirka Laavola, Riina Nieminen, Mun Fei Yam, Amirin Sadikun, Mohd Zaini Asmawi, Rusliza Basir, Jukka Welling, Heikki Vapaatalo, Riku Korhone. Eeva Moilanen / Planta Med 2012; 78(08): pp 779-786 / DOI: 10.1055/s-0031-1298458
Urinary metabolomics study on the protective role of Orthosiphon stamineus in Streptozotocin induced diabetes mellitus in rats via 1H NMR spectroscopy / Amalina Ahmad Azam, Raghunath Pariyani, Intan Safinar Ismail, Amin Ismail, Alfi Khatib, Faridah Abas, and Khozirah Shaari / BMC Complementary and Alternative MedicineBMC series, 201717:278 / https://doi.org/10.1186/s12906-017-1777-1
POTENTIAL LEAF EXTRACT Orthosiphon aristatus AS GROWTH INHIBITOR OF Candida albicans
Constituents of the Vietnamese Medicinal Plant Orthosiphon stamineus / Yasuhiro TEZUKA, Pavlos STAMPOULIS, Arjun H. BANSKOTA, Suresh AWALE,a Kim Qui TRAN, Ikuo SAIKI, and Shigetoshi KADOTA / Chem. Pharm. Bull., Nov 2000; 48(11): pp 1711—1719

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