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Family Campanulaceae
Ligam
Wahlenbergia marginata (Thunberg) A.DC.
ASIATIC BELLFLOWER
Lan hua shen

Scientific names Common names
Adenophora microsperma marginata Y.Y.Qian Ligam (Igorot)
Campanopsis androsacea var. polymorpha Kuntze Asiatic bellflower (Engl.)
Campanopsis androsacea var. rigida Kuntze Southern rockbell (Engl.)
Campanopsis marginata (Thunb.) Kuntze  
Campanopsis marginata var. polymorpha Kuntze  
Campanopsis marginata var. rigida Kuntze  
Campanula agrestis Wall.  
Campanula dehiscens Roxb. ex Wall.  
Campanula indica (A.DC.) D.Dietr.  
Campanula lavandulifolia Reinw. ex Blume  
Campanula marginata Thunb.  
Lightfootia gracilis var. lavandulifolia (Reinw. ex Blume)  
Wahlengergia agrestis (Wall.) A.DC.  
Wahlengergia bivalvis Merr.  
Wahlengergia dehiscens (Roxb. ex Wall.)  
Wahlengergia gracilis var. misera Hemsl.  
Wahlengergia indica A.DC.  
Wahlengergia lavandulifolia (Reinw. ex Blume) A.DC.  
Wahlengergia marginata (Thunb.) A.DC.  
Wahlengergia marginata (Thunb.) A.DC. is accepted. KEW: PLants of the World Online

Other vernacular names
CHINESE: Lan hua shen, Hsi-yeh-sha-shen.
INDONESIAN: Angkeb, Patikan (Javanese), Jukut riut (Sundanese).
MARATHI: Kerdi.
VIETNAMESE: Sam ruong.

Gen info
- Wahlenbergia is a genus of around 260 species of flowering plants in the family Campanulaceae. Species are perennial or annual herbs with simple leaves and blue to purple bell-shaped flowers, usually with five petals.
- In 1814, Heinrich Schrader first used the name Wahlenbergia elongata, but the name was a nomen nudum (unpublished). The genus was first formally described in 1821 by Albrecht Wilhelm Roth and the description published in Roth's Novae Plantarum Species prasertim Indiae Orientalis. Roth kept Schrader's name Wahlenbergia, which honors Göran Wahlenberg, a Swedish botanist. (3)
- Etymology: Genus name Wahlenbergia honors the Swedish naturalist, Göran Wahlenberg . The species epithet 'marginata' derives from Latin 'marg(in)' meaning 'border, edge', referring to where the plant is grows as it is commonly found along roadsides and disturbed areas. (8)

Botany
Wahlenbergia marginata is a perennial herb 3-60 cm tall, glabrous or hairy, woody at base. Leaves arranged spirally, simple, linear to elliptical, 1.5-5.5 cm × 0.1-0.5 cm, decreasing in size upwards, serrate to almost entire, mostly sessile; stipules absent. Inflorescence a 1-few-flowered, terminal or axillary raceme, with small bracts. Flowers bisexual, regular, 3-5-merous, distinctly protandrous; pedicel 1-15 cm long; calyx lobes 0.8-4 mm long; corolla tube 1-5 mm long, lobes ovate or elliptical, 1-7 mm long, acute or acuminate, violet-blue or white; stamens alternating with corolla lobes, free; ovary inferior, obconical to bell-shaped, 1-5 mm long, 2-3-celled, style 1.5-5 mm long, stigma 2-3-lobed. Fruit an obconical to bell-shaped capsule 1.5-10 mm × 1-5 mm, 2-3-valved, many-seeded. Seeds ellipsoid to triangular, up to 1 mm long, shining. (1)

Distribution
- Native to the Philippines.
- Also native to Assam, Bangladesh, China, Himalaya, India, Japan, Jawa, Kazan-retto, Korea, Laos, Lesser Sunda Is., Maluku, Myanmar, Nansei-shoto, Nepal, New Guinea, Ogasawara-shoto, Sri-Lanka, Sulawesi, Taiwan, Thailand, Vietnam.
(2)

Constituents
- Study of methanol extract isolated wahlengergioside, a new hydroxymethylglutaroyl phenylpropanoid glucoside, and a known compound, lobetyolin. (4)
- Repeated column chromatography of aqueous methanol extract of whole plant isolated five compounds: Wahlenoside, a new natural product (1), demethyl syringin (2), 3,5-dihydroxyphenethyl alcohol 3-O-β-D-glucopyranoside (3), rutin (4), and isovitexin (5). (see study below) (9)

Properties
- Due to small size, plant is difficult to locate. Without flowers blooming, it is easily overlooked. (8)
- Studies have suggest hepatoprotective properties.

Parts used
Roots, whole plant.

Uses

Folkloric
- Used for pulmonary infections.
- In Indonesia, used to treat skin eruptions.
- In Cambodia, Laos, and Vietnam, used to treat pulmonary infection.
- In Java, used to treat skin diseases.
- In China, used for treatment of hepatitis.
- In China and Indo-China, roots used for cough and hemoptysis and for treatment of gastralgia.
- In Uttar Pradesh, India, paste prepared from whole plant used for skin troubles.
- In India, roots used for pulmonary infections. Herb used externally for skin diseases and strengthening loose teeth. (7)

Studies
Biotechnology and Secondary Metabolites / Roots:
Wahlenbergia marginata hairy roots were induced by infection with Agrobacterium rhizogenes ATCC 15834 and MAFF 03-01724 strains. The hairy roots produced high content of polyacetylenes, particularly the monoglucoside, lobetyolin. Agrobacterium-mediated gene transformation is an applicable method for getting useful transgenic W. marginata plantlets. (5)
Hepatoprotective / Whole Plant: Study evaluated the hepatoprotective effect of aqueous methanol extract of whole plant of W. marginata against acute liver injury induced by Concanavalin A in mice. marginata. The extracts of W. marginata reduced the ALT/AST in blood serum of mice with acute liver injury, and relieved the damage in liver tissue. In search of active compounds, repeated column chromatography isolated five compounds: Wahlenoside, a new natural product (1), demethyl syringin (2), 3,5-dihydroxyphenethyl alcohol 3-O-β-D-glucopyranoside (3), rutin (4), and isovitexin (5). (9)

Availability
Wild-crafted.

November 2022

                                                 PHOTOS / ILLUSTRATIONS
IMAGE SOURCE: Photograph: Wahlenbergia marginata--blue flower with white center / Douglas Goldman, USDA  / CC by NC 4.0 /  click on image to go to source page / North Carolina Plant Toolbox: Extension Gardener
OTHER IMAGE SOURCE: Photo: Wahlenbergia marginata / © Copyright Bobby Hattaway / DiscoverLife

Additional Sources and Suggested Readings
(1)
Wahlengergia marginata (Thunberg) A.DC. / PROSEA: Plant Resources of South-East Asia
(2)
Wahlengergia marginata (Thunb.) A.DC. / KEW: PLants of the World Online
(3)
Wahlengbergia / Wikipedia
(4)
Wahlengergioside, a phenylpropanoid glucoside from Wahlengergia marginata /  Wei Guang Ma, Ren Xiang Tan, Nicola Fuzzati, Qing Sheng Li, Jean-Luc Wolfender, Kurt Hostettmann / Phytochemistry, 1997; 45(2): pp 411-415
(5)
Biotechnology and secondary metabolites in Wahlenbergi marginata / Ishimaru K, Yamakawa T, Shimomura K, Ando M / Recent Research Developments in Phytochemistry, 2000, Vol 4: pp 23-40
(6)
A survey of traditional medicinal plants of Uttar Pradesh (India) used in treatment of infectious diseases / Achuta Nand Shukla, Sharad Srivastava, AKS Rawat / Nature and Science, 2013; 11(9): pp 24-36 /
ISSN: 1545-0740
(7)
Wahlenbergia marginata (Thunb) A.DC / C. Khare / Indian Medicinal Plants / DOI: 10.1007/978-0-387-70638-2_1765
(8)
Wahlenbergia marginata / North Carolina Plant Toolbox: Extension Gardener
(9)
Hepatoprotective activity and chemical constituents of the aqueous methanol extract of Wahlenbergia marginata / Zhou Xiang=Wem. Qi Yan, Tan Wen-Hong et al / Guihaia, 2016; 36(11): pp 1376-1381 /
ISSN: 1000-3142 / CN 45-1134/Q
(10)
(11)

Sorting Passiflora names / /Maintained by: Michel H. Porcher / MULTILINGUAL MULTISCRIPT PLANT NAME DATABASE / Copyright © 1995 - 2020 / A Work in Progress. School of Agriculture and Food Systems. Faculty of Land & Food Resources. The Univers ity of Melbourne. Australia.

(2)
Sorting Eragrostis names / /Maintained by: Michel H. Porcher / MULTILINGUAL MULTISCRIPT PLANT NAME DATABASE / Copyright © 1995 - 2020 / A Work in Progress. School of Agriculture and Food Systems. Faculty of Land & Food Resources. The University of Melbourne. Australia.

α(5)

DOI: It is not uncommon for links on studies/sources to change. Copying and pasting the information on the search window or using the DOI (if available) will often redirect to the new link page. (Citing and Using a (DOI) Digital Object Identifier)

PHOTOS / ILLUSTRATIONS
                                                            List of Understudied Philippine Medicinal Plants
α(5)

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