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Family Polypodiaceae
Pagong-pagongan
Pyrrosia piloselloides (L.) M.G. Price
DRAGON SCALES
Bao shu lian

Scientific names  Common names 
Drymoglossum piloselloides (L.) C.Presl. Lagolo (Tag.) 
Drymoglossum rotundifolium C.Presl. Lapole (Tag.) 
Lemmaphyllum piloselloides (L.) Luerss. Likup-likup (C. Bis.)
Notholaena piloselloides (L.) Kaulf. ex Kaulf. Piai (Agusan)
Oetosis piloselloides (L.) Kuntz. Pagong-pagongan (Tag,)
Pteris piloselloides L. Pakupakuan (Tag.)
Pteropsis piloselloides (L.) Desv. Dragon scales (Engl.)
Pyrrosia piloselloides (L.) M.G. Price Dragon's scale fern (Engl.)
Taenitis piloselloides (L.) R.Br.  
Lagolo is a common name shared by (1) Acrostichum aureum and (2) Drymoglossum heterophyllum, pagong-pagoñgan.
Drymoglossum piloselloides (L.) C. Presl is a synonym of Pyrrosia piloselloides (L.) M.G. Price. The Plant List
Pyrrosia piloselloides (L.) M.G. Price is an accepted name. The Plant List

Other vernacular names
BANGLADESH: Tenga-chara.
CHINESE: Bao shu lian.
MALAYALAM: Settatali.
MALAY: Sisek naga, Sakat ribu-ribu.

Botany
Pagong-pagongan is a climbing epiphyte with slender rhizomes covered with peltate scales, creeping on trunks and branches. Fronds are of two kinds: sterile and fertile. Sterile fronds vary from elliptic to round, 1 to 5 centimeters long, 1 to 2 centimeters wide, with a rounded apex and a cuneate base. Fertile variety is narrower, 3 to 15 centimeters long, 3 to 10 millimeters wide, on stipes up to 2 centimeters long. Sori are arranged in a broad and submarginal line, not rarely filling the whole surface of the fertile frond.

Distribution
- Common throughout the Philippines. from Cagayan, Nueva Viscaya, Apayao, Bontoc and Benguet, Pangasinan, Laguna, Tayabas and the Camarines Provinces in Luzon; from Panay, Leyte, Negros and Bohol; and from Davao, Cotobato, Lanao, and Agusan Provinces in Mindanao.
- Also reported from India and Malaya, and from Indo-China to New Guinea.

Properties
- Styptic.
- Studies suggest antibacterial and antifungal properties.


Parts used
Leaves.

Uses
Folkloric
• Ground leaves are used as styptic for coagulating blood and arresting capillary hemorrhages.
• Also used for eczema, for conditions referred to as 'agihap.'
• Leaf decoction used for making a lotion for small pox.
• Decoction of leaves used as poultice for headaches.
• Leaves also applied to " bukol" areas, i.e., small subcutaneous lumps and nodes.

• Leaves are crushed and externally applied for pain. Decoction of leaves taken internally two or three times daily for body pains.
• In Mount Manunggal vicinity, Cebu, Philippines, plant is burned and mashed, applied to areas infected with Herpes zoster and other herpetic diseases.
• In Indonesia, used for breast cancer.
• In Malaysia, decoction of plant taken orally to treat cough, diarrhea, and gonorrhea. Decoction of plant also used as bath to treat shingles and ringworm. (6) The Jah Hut peoples in Malaysia use the leaves to relieve pain: crushed as external application or as decoction drunk two or three times daily. (7)
• In Bangladesh, leaves used for earache. (13)
• Gargle made from leaves boiled in water used for thrush.

Studies
Antibacterial:
Study was done on the antibacterial activity of water, ethanol and chloroform extracts of Dp against E coli, S pneumoniae and S aureus. Antibacterial activity against gram-positive bacteria was detected only in the water extract. (1)
Antifungal: Study showed the chloroform and ethanol extract of Dp possessed mild activity against Trichophyton spp. The water extract was devoid of antifungal activity. The antifungal activity was less potent than griseofulvin, fluconazole and itraconazole. Future studies may produce a potential for the treatment of Athlete's foot. (4)
Cytotoxicity Against Leukemia Cells / Leaves: Study evaluated the cytotoxicity of a methanol extract of sisek naga leaf (Drymoglossum piloselloides) against leukemia cells P388. Results showed cytotoxic effects against leukemia cells with a 50% inhibition of cell growth (19.32 µg/mL). (7)
Cytotoxicity / Antioxidant / Leaves: Study evaluated the cytotoxic effect of various extracts of P. piloselloides on MCF-7 breast cancer cell and in vitro antioxidant activity. Results showed the dichlormethane extract has highest antioxidant activity by DPPH assay with IC50 value of 28.29 µg/ml. Cytotoxicity (MTT assay) showed the FVIEDCMP with the greatest IC50 value of 28.73 µg/mL. Results showed P. piloselloides has potential as antioxidant and anticancer drug. (
9)
Antipyretic / Anti-Inflammatory: In a study of 15 species of Philippine medicinal pteridophytes evaluated for antimicrobial, antipyretic and anti-inflammatory activities, Pyrossia piloselloides, showed significant antipyretic activity in yeast-induced pyrexia and anti-inflammatory activity in egg albumin induced rat paw edema. (
11)

Availability
Wild-crafted.

Last Update January 2017

Photo © Godofredo Stuart / StuartXchange

Additional Sources and Suggested Readings
(1)
In vitro Antibacterial Activity of Drymoglossum piloselloides L. Presl / M.S. Nazrul Hakim, M. Zarina et al /
(2)
In vitro Anti-fungal Activity of Drymoglossum piloselloides Against Several Fungi Responsible for Athlete's Foot /

(3)
Drymoglossum piloselloides (L.) C. Presl / Chinese name / Catalogue of Life, China
(4)
In vitro anti-fungal and anti-bacterial activity of Drymoglossum piloselloides L. Presl. against several fungi responsible for Athlete's foot and common pathogenic bacteria / M. N. Somchit*, H. Hassan, A. Zuraini, L. C. Chong, Z. Mohamed and Z. A. Zakaria / African Journal of Microbiology Research Vol. 5(21), pp. 3537-3541, 9 October, 2011
(5)
Pyrrosia piloselloides / Synonyms / EOL
(6)
The Use of Medicinal Plant Species by the Temuan Tribe of Ayer Hitam Forest, Selangor, Peninsular Malaysia / FARIDAH HANUM and NURULHUDA HAMZAH / PertanikaJ. Trap. Agric. Sci. 22(2): 85 - 94 (1999)
(7)
Ethnobotanical Study of Medicinal Plants Used by the Jah Hut Peoples in Malaysia
/ K. W. Lin / Indian Journal of Medical Sciences
(8)
Uji Sitotoksisitas Ekstrak Metanol Daun Sisik Naga (Drymoglossum piloselloides Presl.) terhadap Sel Leukemia P388 / Anwar Sahida*, Dingse Pandiangana, Parluhutan Siahaana, Marhaenus J. Rumondora / JURNAL MIPA UNSRAT ONLINE 2 (2) 94-99
(9)
In Vitro Antioxidant and Cytotoxicity Activity of Extract and Fraction Pyrrosia piloselloides (L) M.G Price / E. T. Wulandari; B. Elya; E. Hanani; J. A. Pawitan / International Journal of PharmTech Research;Jan-Mar 2013, Vol. 5 Issue 1, p 119-125
(10)
Ethnobotany of Medically Important Plants in Mt. Manunggal and Its Vicinity / Maria Lilibeth P. Abaquita, Inocencio E. Buot
(11)
Antimicrobial, Antipyretic, and Anti-Inflammatory Activities of Selected Philippine Medicinal Pteridophytes / Victor B. Amoroso, Dorothy A. Antesa, Dave P. Buenavista, Fulgent P. Coritico / LDCU-RPO-Asian Scientific Journals, Vol 5, No 1, 2012.
(12)
Pyrrosia piloselloides / Synonyms / The Plant List
(13)
MEDICO-BOTANICAL REPORT ON THE CHAKMA COMMUNITY OF BANGLADESH / SNIGDHA ROY, MOHAMMAD ZASHIM UDDIN, MD. ABUL HASSAN AND M. MATIUR RAHMAN / Bangladesh J. Plant Taxon. 15(1): 67-72, 2008 (June)
(14)
Ethnobotany of Medically Important Plants in Mt. Manunggal and Its Vicinity / Maria Lilibeth P. Abaquita, Inocencio E. Buol, Jr. /
(15)



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