Pakopatoti-alog is a hairy, branched herb, spreading from the roots and growing up to 70 centimeters high. Buds are white and wooly. Leaves are alternate, stalkless, sinuately pinnatifid, and divided into toothed lobes. Flowering heads are borne opposite the leaves, and are short-peduncled, rounded, and 8 to 10 millimeters in diameter. Flowers are small, very numerous, and yellow. Involucral bracts are ovate, thick, rigid, and hairy. Achenes are cylindric, glandular, and about 2 millimeters long. Pappus-hairs are connate, ending in a short, fimbriate tube.
- An occasional weed in open, waste places in and about towns.
- In La Union, Pampanga, Bulacan and Rizal Provinces in Luzon.
- Introduced, also occurring in tropical and subtropical Asia and Africa.
- Study isolated a diterpenoid from the acetone extract - 8-hydroxy-13E-labdane-15yl-acetate.
- Study of the whole plant isolated two new 5-deoxyflavones, 6-hydroxy-2′,4′,5′-trimethoxyflavone and 6-hydroxy-3′,4′,5′-trimethoxyflavone, together with a known flavone, 7,2′,4′-trimethoxyflavone.
- Study of whole plant isolated two new bioactive flavones: 5-deoxyflavones, 6-hydroxy-2′,4′,5′-trimethoxyflavone (1), 6-hydroxy-3′,4′,5′-trimethoxyflavone (2) and a known flavone, 7,2′,4′-trimethoxyflavone (3). (7)
Analgesic, stomachic, antiseptic, antispasmodic.
- In the Philippines, leaf infusion used as stomachic and antispasmodic.
- In India leaves are a valuable stomachic with deobstruent and antispasmodic properties. Also, prescribed as an infusion and electuary for obstructed menses and hysteria.
- Leaves sometimes used in antiseptic and anodyne preparations.
• Analgesic: Study of methanol extract of the whole plant of Grangea maderaspatana showed a dose-dependent analgesic activity. (1)
• Antioxidant / Free Radical Scavenging: Study showed antioxidant activity that was concentration dependent, increasing with the amount of extract. Free radical scavenging and antioxidant activities may be attributed to the presence of phenolic and flavonoid compounds. (2)
• Estrogenic / Anti-implantation Efficacy: A mixture of flavonoids extracted from G. maderaspatana showed estrogenicity and antiimplantational activities in a mouse study. (4)
• Diterpenoid: Study of acetone extract yielded a new diterpenoids: 8-hydroxy- 13E-labdane-15yl-acetate.