Zebrina pendula is a vigorous branching
creeper with succulent leaves and stems, rooting freely at the nodes.
Leaves are sessile and alternate, ovate and short acuminate, the upper surface dark green to
purple, with 2 longitudinal silver stripes adaxially. The under-surface is purple. Flowers
are small and purple.
- Popular as a ground cover, tending to become invasive.
-Native to Mexico.
- Study isolated three components from Zp: ß-sitosterol, 3β, 5α, 6β-trihydroxy stigmast and succinic acid. (see study below) (7)
- Studies have shown anti-proliferative properties.
Leaves and stems.
- No reported
folkloric medicinal use in the Philippines.
- Elsewhere, used for treatment of common cold, hypertension, tuberculosis,
- In Jamaica, used for
treatment of high blood pressure, coughs, tuberculosis, and as cold cure.
- In combination with other herbs, used to purify the blood and for amenorrhea.
- In China, leaves applied to reduce swellings. Also used for hemorrhoids, blood in the stools, tuberculous cough, conjunctivitis, kidney infections.
- Leaves mixed with other types of herbs as a blood tonic and to treat amenorrhea.
- In Mexico, Matali, a beverage made of lemon and sweetened decoction of leaves, is used as a cold tonic drink.
- In Afro-Cuban Santeria, decoction of leaves drunk to flush gravel out of the kidneys and bladder, break the crisis of colitis, and provoke menstruation. (Cabrera, 1971) (5)
• 3-Ecdysone / Anti-Arrhythmic Effect: Study isolated ß-ecdysone from Z. pendula, and in animals has shown elimination of arrhythmia induced by aconitine. (2)
• Antineoplastic Components: Study isolated three components identified as β-sitosterol, 3β, 5α, 6β-trihydroxy stigmast and succinic acid. Anti-tumor activity was seen in ascites-type-180 sarcoma of mice: 43% (160mg/kg) for succinic acid, 91% (100mg/kg) for β-sitosterol and 98%(100mg/kg) for 3β, 5α, 6β-trihydroxystigmast. (3)
• Anti-Cancer / Anti-Proliferative: Study evaluated the anticancerous properties of Tz extracts against two cancer cell lines, A-549 lung carcinoma and SCC-13y malignant keratinocyte cells. Tz treatment resulted in decreased cellular growth. Tz treatment was also tested on non-cancerous cell line of HFF-human foreskin fibroblasts cells to determine relative toxicity of the extract. Results showed inhibitive effects of Tz extracts on cancerous and non-cancerous cells. (6)
• Antineoplastic Components: Study isolated three components from Zp: ß-sitosterol, 3β, 5α, 6β-trihydroxy stigmast and succinic acid. Anti-tumor rates were 43% (160mg/kg) for succinic acid, 91% (100 mg/kg) for ß-sitosterol, and 98% (100 mg/kg) for 3β, 5α, 6β-trihydroxystigmast in anti-cancer test of ascites type-180 sarcoma of mice. (7)
• Effect on Human Cancer Cells: Study evaluated the anticancer characteristics of Tradescantia zebrina and Tradescantia fluminensis. Study confirmed the general inhibitory effects of T. zebrina and T. fluminensis extracts on cancerous and non-cancerous cells. (8)