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Family Menispermaceae
Silong-pugo
Pericampylus glaucus (Lam.) Merr.

BROAD-LEAVED MOONSEED
Xi yuan teng

Scientific names   Common names  
Pericampylus glaucus Merr. Botang-botang (C. Bis.)
Menispermum glaucum Lam.  Gapisilid (Sub.)
Cocculus glaucus DC. Hah-un (Yak.)
Cocculus incanus Colebr. Ha-un (Sul.)
Pericampylus incanus Miers. Lagauat (Bag.)
  Pamago (Bik.)
  Pisok (Ig.)
  Silong-pugo (Tag.)
  Tugian-tugian (Tag.)
  Broad-leaved moonseed (Engl.)
  Xi yuan teng (Chin.)

Other vernacular names
CHINESE: Guang teng.
INDONESIA: Areuy geureung (Sundanese), Celuru (Javanese), Akar gamat (Moluccas).
MALAYSIA: Gasing gasing, Kelempenang, Taworuk.
THAI: Salit hom kha, Yan tap tao.
VIETNAM: Ch[aa]u d[ar]o, D[aa]y l[ox]i ti[eef]n.

Botany
Silong-pugo is a climbing shrub, with hairy branchlets when young. Leaves are thin, pale or subglaucous beneath, broadly ovate or nearly round, 5 to 8 centimeters wide, truncately rounded or heart-shaped at the base, sometimes slightly peltate, and pointed at the apex, with 5 basal nerves, and tomentose. Cymes or panicles are 2- to 3-chotomous. Flowers are numerous and yellow. Fruit is rounded, pea-sized, red or purplish, becoming black when ripe. Seeds are kidney-shaped, with crested edges.

Distribution
- Throughout the Philippines in open thickets at low and medium altitudes.
- Also reported in India through Malaya to the Moluccas.

Constituents
- Study yielded 5 triterpenes: hopenone-B, hopenol-B, 22-hydroxyhopan-3-one, erythrodiol 3-palmitate, and 5β,24-cyclofriedelan-3-one.

Properties
- Roots are narcotic; contains an alkaloid.

Parts utilized:
Leaves and roots.

Uses
Folkloric
- Roots used as antidote for snake bites.
- Leaves applied to the head for headaches.
- Also used for asthma and coughs.

- In China, leaves used for treatment of tumors, itches, tetanus, eclampsia.

Studies
Periglaucines / Anti-Hepatitis B / Anti-HIV Alkaloids: Study isolated four new hasubanane-type alkaloids, periglaucines A-D (1-4) and three known alkaloids. Alkaloids 1-4 inhibited hepatitis B virus (HBV) surface antigen (HBsAb) secretion. Two alkaloids, norruffscine and (-)-8-oxotetrahydropalmatine, exhibited inhibitory activity against HIV-1. (1)
Chemical Constituents: Study of rhizomes yielded six cyrstalline substances: epifriedelinol, mellisic acid, palmatic acid, stearic acid, bututic acid and daucosterol. (2)
Triterpenoidal Constituents / Antitumor Activity: Study yielded five triterpenes. Compound 4, erythrodiol 3-palmitate, inhibited the proliferation of K562 cells. (3)

Availability
Wild-crafted.

Last Update June 2013

MAGE SOURCE: / Illustration / Pericampylus glaucus (Lam.) Merr. [as Folium lunatum minus] Rumphius, G.E., Herbarium amboinense, vol. 5: p. 40, t. 25, fig. 1 (1747) / PlantIllustrations.org
SOURCES

Additional Sources and Suggested Readings
(1)
Periglaucines A-D, Anti-HBV and -HIV-1 Alkaloids from Pericampylus glaucus
/ Yan MH, Cheng P, Jiang ZY, Ma YB, Zhang XM, Zhang FX, Yang LM, Zheng YT, Chen JJ / Journal of natural products 71(5):760-3, 2008 May

(2)
Chemical constituents of Pericampylus glaucus (Lam.) Merr./ Liang P, Zhou Q, Zhou F. / Zhongguo Zhong Yao Za Zhi. 1998 Jan;23(1):39-40, 63.
(3)
Triterpenoidal constituents of Pericampylus glaucus and their antitumor activity in vitro / Zhao Wei-quan, Cui Cheng-bin / Chinese Journal of Medicinal Chemistry, 2009-03
(4)
Pericampylus glaucus (Lam.) Merr. (accepted name) / Chinese names / Catalogue of Life, China
(5)
Pericampylus glaucus (Lamk) Merr. / Vernacular names / GLOBinMED
(6)
Secondary Metabolites and Their Anti-tumor Activity from Pericampylus Galucus and Three Actinomycetic Antibiotic-resistent Strains / ZhaoWeiQuan / Thesis, 2008

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