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Family Myrsinaceae
Ardisia elliptica Thunb.

Dong fa zi jin jiu

Scientific names Common names
Ardisia elliptica Thunb. Apiot (Mbo.)
Ardisia kotoensis Hayata Babagion (C. Bis.)
Ardisia littoralis Andrews Butau (Bik.)
Ardisia sorsogonensis Elmer ex Merr. Dandulit (Sul.)
Ardisia squamulosa C.Presl Kanai (Tagb.)
Ardisia umbellata Roxb. Katagpo (Tag.)
Bladhia elliptica (Thunb.) Nakai Katagpok (Tag.)
Bladhia kotoensis (Hayata) Nakai Katatbun (Tag.)
Bladhia squamulosa (C.Presl) Nakai Katiñgi (Bon.)
Tinus squamulosa (C.Presl) Kuntze Kodang (Mbo.)
  Kolagpung-pula (Sbl.)
  Kolen (Ilk.)
  Koleng (Ilk.)
  Liputing-gubat (Tag.)
  Lunidang (Tag.)
  Malasiak (Bik.)
  Malayambis (Tag.)
  Mampa (Neg.)
  Maramaatam (Ibn.)
  Mulang (Ibn.)
  Oksor (Ilk.)
  Pamutul (Sbl.)
  Panghas (P. Bis.)
  Paninglon (Sbl.)
  Pataktol (Pamp.)
  Piñgil (Neg.)
  Pognaan (Mbo.)
  Sirapian (Bik.)
  Tagpo (Tag., Bik., C. Bis., Sul.)
  Tagpung-pula (Tag.)
  Takpo (Bik.)
  Tamil (C. Bis.)
  Tayupo (C. Bis.)
  Tukal (Tag.)
  Turo (Pamp.)
  Duck's eye (Engl.)
  Elliptical-leaf ardisia (Engl.)
  Seashore ardisia (Engl.)
  Shoebutton ardisia (Engl.)
Tagpo is a shared common name of two species of plants: (1) Tagpong-gubat, tagpo(Psychotria luconiensis), and (2) Tagpo (Ardisia squamulosa Presl). The latter is a small tree growing to a height of about 10 meters, with fragrant white or pink flowers, and blue or purplish rounded 5-8 mm fruits.
Ardisia elliptica Thunb. is an accepted name. The Plant List

Other vernacular names
CHINESE: Lan yu zi jin niu, Dong fa zi jin niu.
INDIA: Bisi, Kadna, Katapenga, Bugadi, Manipudbam, Kozhkkottai, Narikandam, Kaka-njara, Bodhina gida, Shuli, Bode, Sore, Banjam, Kuti, Damaai phal.
MALAYSIA: Buah letus, Cempenai, Lempenai, Mempenai, Penai, Penah, Periah, rempenai, Daun bias hati, Kayu lampilan, Mata pelandok, Mata ayam, Mata itek.
NEPAL: Damai phul.

Tagpo is a small tree reaching a height of about 10 meters. Leaves are alternate, oblanceolate to elliptic-oblanceolate, 6 to 15 centimeters long, 2 to 6 centimeters wide, and pointed at both ends. Flowers are white or pink, fragrant, borne on compound, terminal or lateral inflorescences, and about 1 centimeter in length. Fruit is dark blue or purple, rounded, and 5 to 8 millimeters in diameter.

- Common in primary forests at low and medium altitudes, ascending to 1,000 meters throughout the Philippines.
- Occurs in India, Sri-Lanka, Indo-China, Malaysia, Indonesia and New Guinea.

- Leaf extract yield ß-amyrin
compared to 0.098% in fresh leaves. (see study below) (14)
- Methanol extracts of fruits and leaves yielded similar major compounds viz. 5-hydroxymethyl-2-furancarboxaldehyde with percentage area of 58.42% and 45.13% respectively; and 2,4-di-tert-butylphenol with 3.04% and 20.87%. (see study below) (15)
- Study of ethyl acetate extract of leaves isolated three compounds: 5-pentadecylbenzene-l,3-diol or 5-pentadecylresorcinol (1), α-amyrin (2) and taraxerone (3). (20)
- Fruits contain a quinone derivative, embelin, as major constituent. There constituents reported are myricetin, quercetin, berginin, norberginin, kaempferol quercetin 3-O-ß-d-glucopyranoside and gallic acid. (23)

- Vulnerary, febrifuge, anti-diarrheal.
- Studies have suggested antiviral, antibacterial, antioxidant, anti-platelet aggregation, anti-diarrheal, anti-spermatogenic properties.

Parts used


Edibility / Culinary
- Leaves and young shoots eaten as vegetable; used as greens for salad or cooked with meat or fish.
- Flowers and fruits cooked as flavoring for fish.
- In the Malay Peninsula, young shoots are eaten.
- In the Philippines, leaves used on wounds.
- Malays use a decoction of leaves for treatment of chest pains, fever, diarrhea, and parturition problems; roots may be substituted for the same use.
- The Malays use a decoction of leaves to treat heart pains. (19)
- Leaves used to treat scabies and intestinal worms.
- Plant used for liver poisoning, fever, diarrhea, gonorrhea, venereal diseases, and complications of parturition.

Health-Promoting Compounds / Phytopharmaceuticals:
Species of Ardis are rich sources of novel and potent phytochemical compounds, such as bergenin and ardisin. Report reviews the usage and biological activities of Ardisia compounds. (1)
Anti-Herpes Simplex Virus / Anti-Adenovirus: In a search for new antiviral agents from traditional medicine, the hot water extracts of 12 traditionally used medicinal plants in Taiwan, including Ardisia squamulosa, showed anti-HSV and anti-ADV activities. A. squamulosa was more effective in inhibiting ADV-8 replication than the other four viruses. (2)
Antibacterial / Anti-Salmonella / Dried Fruits: Study of dried fruit extracts yielded three compounds, viz., syringic acid, isorhamnetic and quercetin, which showed activity against veterinary Salmonella. The minimal inhibitory concentrations (MICs) of the isolated compounds ranged between 15.6 and 125.0 µg/mL. (4)
Antiplatelet / α- and ß-Amyrin: A methanol extract yielded two compounds, viz., α- and ß-amyrin, and screened for antiplatelet activity. The pharmacokinetics and multivariate date analysis predicted both α- and ß-amyrin to be antiplatelet. (7)
ß-Amyrin vs Aspirin in Inhibition of Platelet Aggregation: Study investigated the effect of fresh leaves extracts of A. elliptica on collagen induced platelet aggregation and to isolate and purify potential antiplatelet components. Fractionation isolated and purified ß-amyrin. Results suggest ß-amyrin was the bioactive component, which was more potent than aspirin in inhibiting collagen-induced platelet aggregation. (8)
Antioxidant: Study evaluated the antioxidant activities in Syzygium cumini and Ardisia ellipitica using various assays in relation to total flavonoid, phenolic, and anthocyanin contents. Total flavonoid content and anthocyanin content exhibited a very strong relationship with FRAP, ABTS, and DPPH scavenging activities, and A. elliptica showed better in chromatic properties compared to Syzygium cumini. (9)
Antimicrobial: Study has shown Ardisia elliptica to have antimicrobial activity. A hexane extract of leaves yielded hydrocarbons, apolar and polar fatty esters, triterpenoid alcohols (bauerenol, α- and ß-amyrin), sterols (ß-sitosterol) and polar compounds. Polar fraction showed most effective activity against P. aeruginosa and nine other bacteria. (10)
Anticancer Activity: Ardisia elliptica plant extract was 1 of 9 Thai medicinal plants that exhibited antiproliferative activity against SKBR3 human breast adenocarcinoma cell line using MTT assay. (10)    (18)
Antidiarrheal / Antioxidant / Fruits: Study evaluated a crude ethanol extract of fruits for antioxidant and antidiarrheal activities. Results showed significant DPPH radical scavenging activity. The extract also showed a significant protection against experimentally induced diarrhea by castor oil and magnesium sulfate. (11)
Toxicity Testing / Fruits: Study evaluated the safety of an ethanolic extract of A. elliptica fruits in animal models. Results showed no acute or subchronic toxicity in experimental animals. (12)
Effect on Spermatogenesis / Decreased Epididymal Sperm Count / Leaves: Study on male rats examined the effects of a hexane leaf extract on epididymal sperm count, viability and aberration. Results showed a significant decline in epididymal cell count with negligible effect on sperm morphology and viability. (13)
Antiplatelet and Anticoagulant Effects / Leaves: Study investigated the potential antiplatelet and anticoagulant effects of ß-amyrin isolated from leaves of A. elliptica in vivo in human blood and ex vivo in SD rats and in vivo effects on tail-bleeding in SD rats. Results showed the leaf extract prolonged bleeding time more than ß-amyrin probably due to the presence of both antiplatelet and anticoagulant compounds in the leaf extracts producing synergistic antithrombotic effects. The ß-amyrin exhibited only antiplatelet effects. (14)
Antibacterial / Antioxidant / Leaves and Fruits: Study of methanol extracts of leaves and fruits showed antibacterial activity against Staphylococcus aureus and Escherichia coli. Anitoxidant assay showed both fruits and leaves extracts decolorized DPPH. (see constituents above) (15)
Alkenylresorcinol / Potent Platelet Activating Factor Antagonist / Leaves: An ethyl acetate fraction of a methanol extract of leaves isolated a new alkenylresorcinol, 5-(Z-heptadec-4'-enyl)resorcinol, together with 5-pentadecylresorcinol. The alkenylresorcinol showed strong inhibitory activity on PAF receptor binding to rabbit platelets. (16)
• Antioxidant / Leaves: Study evaluated the antioxidant activity of various extracts of four Ardisia sp. using DPPH and CUPRAC testing and correlation with total flavonoid, phenolic and carotenoid content in various leaves extracts. Ethanolic leaves extracts of A. elliptica showed the highest phenolic content (29.54 g GAE/100 g. The EA extract of leaves showed the lowest EC50 of CUPRAC with EC50 of 30.34 µg/ml. Results suggest leaves extracts of A. elliptica, A. crenata, A. cymosa, and A. fuliginosa may be exploited as natural antioxidant sources to alleviate oxidative stress. (21)
• Analgesic Activity / Leaves: The dichlormethane extract of air-dried leaves of Ardisia cf. elliptica (subgenus Tinus) yielded a mixture of bauerenol (1a) α-amyrin (1b) and ß-amyrin (1c). On hot-plate assay, 1a-1c showed analgesic activity comparable to drug control Diclofenac. (22)
• Antiproliferative / Humsn Colon Cancer Cell Line / Fruit and Leaves: Study screened ethanolic extracts of 30 Thai edible plants for in vitro antiproliferative effect on HT-116 human colon cancer cell line. Fruit and leaf extract of A. elliptica was one of five plants that exhibited antiproliferative activities. The fruit extract of A. elliptica showed highest antiproliferative activity. (24)
• Comparative Cytotoxicity / Growth Inhibition of HepG2 Cells: Study evaluated the chemical composition and relative anticancer potential of six Ardisia species. Ardisia elliptica showed the third most potent in vitro inhibition of proliferation of HepG2 cells. (25)


Updated January 2020 / November 2017 / February 2017 / February 2015

Photos © Godofredo Stuart / StuartXchange
IMAGE SOURCE: Public Domain / Willughbeia drupacea / Ardisia obovata / Pterospermum diversifolium Blanco1.182-original.png / Flora de Filipinas / 1880 - 1883 / Francisco Manuel Blanco (O.S.A) / Wikimedia Commons

Additional Sources and Suggested Readings
The genus Ardisia: a novel source of health-promoting compounds and phytopharmaceuticals / Hideka Kobayashi and Elvira de Mejia /
Journal of Ethnopharmacology, Volume 96, Issue 3, 15 January 2005, Pages 347-354 / doi:10.1016/j.jep.2004.09.037
In vitro anti-herpes simplex viruses and anti-adenoviruses activity of twelve traditionally used medicinal plants in Taiwan / Lien-Chai Chiang, Hua-Yew Cheng et al / Biological & pharmaceutical bulletin, Vol 26 / 2003 Nov
Ardisia elliptica Thunb. / Catalogue of Life, China, 2010
Anti-Salmonella activity of constituents of Ardisia elliptica Thunb.
/ Methin Phadungkit, Omboon Luanratana / Natural Product Research (2006), Volume: 20, Issue: 7, Pages: 693-696
Ardisia squamulosa C.Presl is a synonym of Ardisia elliptica Thunb.
/ The Plant List
Ardisia elliptica / Vernacular names / GLOBinMED
Chemical and Pharmacological Studies of Ardisia Elliptica: Antiplatelet, Anticoagulant Activities and Multivariate Data Analysis for Drug Discovery / Ching Jianhong / Thesis, 2011 / National University of Singapore
Beta-amyrin from Ardisia elliptica Thunb. is more potent than aspirin in inhibiting collagen-induced platelet aggregation. / Ching J, Chua TK, Chin LC, Lau AJ, Pang YK, Jaya JM, Tan CH, Koh HL. / Indian J Exp Biol. 2010 Mar; 48(3): pp 275-279.
Antioxidant Activities of Syzygium Cumini and Ardisia Elliptica in Relation to Their Estimated Phenolic Compositions and Chromatic Properties / A. M. Siti-Azima, A. Noriham, and M. Nurhuda / IJBBB 2013; 3(4): pp 314-317 ISSN: 2010-3638 / DOI: 10.7763/IJBBB.2013.V3.221
Ardisia elliptica / Edible Medicinal And Non-Medicinal Plants: Volume 4, Fruits / By Tong Kwee Lim / GoogleBooks
Antioxidant and antidiarrheal activities of ethanol extract of Ardisia elliptica fruits / Shubhra Kanti Dey, Arpona Hira, Md. Sariful Islam Howlader, Arif Ahmed, Hemayet Hossain, and Ismet Ara Jahan / Pharm Biol., Feb 2014; 52(2): pp 213-320 / doi:10.3109/13880209.2013.826245
Acute and Subchronic Toxicity Study of Ardisia ellipica Thunb. Fruit Extract / Nalinphat Saktiyasunthorn, Songpol Chivapat, Pornchai Sincharoenpokai, Anudep Rungsipipat, Nongnuth Maneechai, Boonyanee Suphaphon, Aussavashai Shuayprom / The Thai Journal of Veterinary Medicine, 2012; 42(2)
Effects of the oral administration of nonpolar extract from Ardisia squamulosa Presl (Myrsinaceae) leaves on spermatogenesis in rats / Dennis D Raga, Glorina N Pocsidio, Annabelle A Herrera / Pharmacognosy Research, 2011, Vol 3, Issue 4, Pp 260-265.
Drug discovery from Ardisia elliptica / Lee Jun Feng / USP Undergraduate Journal, Volume 4, Issue 1, Jan 2012 | 73
Chemical Constituents and Bioactivity Studies of Ardisia Elliptica / Nurul Zawani Alias, Nur Kamisah, Mohd Ishak / The Open Conference Proceedings Journal, 2014, 5: 1-4
Bioassay-Guided Isolation of a Potent Platelet-Activating Factor Antagonist Alkenylresorcinol from Ardisia elliptica / Juriyati Jalil, Ibrahim Jantan, Khozirah Shaari, and Iftikhar Ahmad Abdul Rafi / Pharmacognosy Biology, 2004; 42(6): pp 457-461 / doi:10.1080/13880200490886157
Ardisia elliptica Thunb. / Synonyms / The Plant List

Antiproliferative activity of Thai medicinal plant extracts on human breast adenocarcinoma cell line.
/ Moongkarndi, P.; Kosem, N.; Luanratana, O.; Jongsomboonkusol, S.; Pongpan, N. / Fitoterapia
2004 75 3/4 375-377 / DOI: 10.1016/j.fitote.2004.01.010
Mata pelandok or Seashore ardisia / Wild Fact Sheets
Chemical constituents of Ardisia elliptica Thunb. [2004] / Juriyati Jalil, Khozirah Shaari / AGRIS: Food and Agriculture Organization of the United Nations
Antioxidant Activities of Various Extracts from Ardisia SP Leaves Using DPPH and CUPRAC Assays and Correlation with Total Flavonoid, Phenolic, Carotenoid Content / Irda Fidrianny*, Wempi Budiana, Komar Ruslan / Article in International Journal of Pharmacognosy and Phytochemical Research 7(4) · August 2015
Analgesic triterpenes from Ardisia cf. Elliptica (Subgenus: Tinus) (Myrsinaceae) / Dennis D. Raga , Marie Luciene S. Diezmos , Abigail Cheska C. Orantia , Marvin James A. Lo, Juan Carlo P. Evangelista , Sang Hyeon Kim , Chien-Chang Shen and Consolacion Y. Ragasa / Der Pharma Chemica, 2014, 6(4):pp 153-161
THE PHARMACOGNOSTIC SPECIFICATION OF ARDISIA ELLIPTICA FRUITS AND THEIR EMBELIN CONTENTS BY TLC IMAGE ANALYSIS COMPARED TO TLC DENSITOMETRY / Pongsathorn Yukongphan, Worathat Thitikornpong, Chanida Palanuvej, and Nijsiri Burangrungal / Bulletin of Health, Science, and Technology, 2013, 11(2)
: pp 21-28
Anticancer Effects of Some Medicinal Thai Plants / Pongtip Sithisarn and Piyanuch Rojsanga / Natural Products and Cancer Drug Discovery / DOI: 10.5772/67648
Comparative in vitro bioactivities of tea extracts from six species of Ardisia andtheir effect on growth inhibition of HepG2 cells / Amanda M.B. Newell, Gad G. Yousef, Mary Ann Lila, Marco Vinicio Ramírez-Mares, Elvira Gonzalez de Mejia / Journal of Ethnopharmacology, 2010; 130: pp 536-544 / doi:10.1016/j.jep.2010.05.051

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