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Family Myrtaceae
Tambis
Syzygium aqueum (Burm.f.) Alston.
WATER ROSE APPLE
Shui lian wu

Scientific names Common names
Cerocarpus aqueus (Burm.f.) Hassk. Tambis (Tag.)
Eugenia aquea Burm.f. Bell fruit (Engl.)
Eugenia callohylla (Miq.) Reinw. ex de Vriese Water apple (Eng.)
Eugenia javanica Lam. Water cherry (Eng.)
Eugenia nodiflora Aubl. Water jambu (Eng.)
Eugenia obversa Miq. Watery rose apple (Eng.)
Jambosa aquea (Burm.f.) DC.  
Jambosa calophylla Miq.  
Jambosa javanica (Lam.) K.Schum. & Lauterb.  
Jambosa madagascariensis Blume  
Jambosa subsessilis Miq.  
Malidra aquea (Burm.f.) Raf.  
Myrtus javanica (Lam.) Blume  
Syzygium aqueum (Burm.f.) Alston  
Syzygium javanicum (Lam.) Masam.  
Syzygium obversum (Miq.) Masam.  
Syzygium aqueum is closely related to S. malacennsis and S. samarangense. They are separate species. There is also a confusing crossover use of "apple" in the common names.
Some copilations separate the Syzygium species as: S. aqueum, Tambis, Bell fruit; S. malacense, Makopang-kalabaw, Malay apple; and S. samarangense, Makopa, Java apple.
Syzygium aquem (Burm.f.) Alston is an accepted speciess. KEW: Plants of the World Online

Other vernacular names
CHINESE: Shui lian wu.
FRENCH: Jambosier d'eau, Jambolanier d'eau, Pomme d'eau, Pomme de Java.
GERMAN: Wachsjambuse, Wasserjambuse.
JAPANESE: Mizu renbu.
MALAY: Jambu air, Jambu ayer, Jambu ayer mawar, Jambu chili, Jambu penawar, Djamboo wer.
PORTUGUESE: Jambu branco, Jambo d'agua, Jambeiro aguado.
RUSSIAN: Sizigium akvum, Sizikhium iablochnyj.
SPANISH: Cajulito soliman, Manzana de agua, Perita-costeña.
TAGALOG: Tambis.
THAI: Chom phu pa, Machomphu-pa.

.

Gen info
- The genus Syzygium belongs to the Myrtaceae family, which consists of 144 genera and 5500 species, with about 1,200 of the species belonging to the genus Syzygium.
- There is continuing confusion on three Syzygium species: S. aqueum, S. malacense, S. samarangense. They are three distinct separate species, sharing in fruit edibility but quite confusing in their common names.
- The two species, Syzygium aqueum and Syzygium samarangense are often confused due to morphological similarities. Study sought to delineate the two confusing taxa, comparing selected laminal and venation characters. While similar characters are shared, laminar size, apex, and base shape, areolation and freely ending veinlets (FEVs) were found to be distinct. (see study below) (29)
- Syzygium aqueum is referred to as water apple, bell fruit and Tambis locally; S. malacense is Malay apple, yambu, Makopang-kalabaw; and S. samarangense is Java apple, wax jambu, Makopa. (8)

Botany
Syzygium aqueum is a tree growing 8- to 10 meters tall, with a short and crooked trunk, 30 29) to 50 centimeters in diameter, often branched near the base and and with an irregular canopy. Leaves are opposite, elliptic-cordate to obovate-oblong, 7 to 25 centimeters long and 2.5 to 16 centimeters wide, sometimes aromatic when bruised. Petioles are 0.5 to 1.5 millimeters long. Inflorescences are terminal and axillary 3- to 7-flowered. Flowers are 2.5 to 3.5 centimeters in diameters, with calyx tube 5 to 7 millimeters long; petal are 4, spathulate, up to 7 millimeters long, yellow-white; stamens 0,75-2 centimeters long. Fruit is a fleshy yellow or red berry, turbinate, 1.5 to 2 centimeters by 2.5 to 3.5 centimeters, crowned by fleshy calyx segments, white to red, glossy; with a watery and juicy flesh. Seeds are 1 to 6, small and rounded. (8)

Other botanical info (S. equeum, S. malacense, S. samarangense)
- While Malay apple can easily be recognized, it is not easy to distinguish between the various water apple (S. aqueum) and wax jambu fruits (Z. samarangense)
- Water apple (S. aqueum) is watery, thirst-quenching, with a glistening, almost transluscent skin, while wax jambu (S. samarangense) is glossy, wax-like, rather dry-fleshed.
- Eighty percent of the fruit is edible. The composition of all 3 species is similar per 100 g edible portion: water >90%, protein 0.3g, fat none, carbohydrate 3.9 g, fiber 1.0 g, vitamin A 253 IU, vitamin B1 ad B2 traces, vitamin C 0.1 mg, energy value 80 J/100g.
- All three species show a lot of seedling variation and several forms are recognized by fruit color (white, green, or pink for wax jambu) and taste (sweet and sour forms of water apple). (8)

Distribution
- Introduced.
- Naturalized in thickets and forests at low and medium elevation.
- Cultivated.

- Native to Andaman Is., Bangladesh, Cambodia, Caroline Is., Laos, Marianas, Myanmar, Nicobar Is., Sri Lanka, Thailand, Trinidad-Tobago, Vietnam. (1)

Constituents
- Study of leaf extracts yielded six flavonoid compounds viz. 4-hydroxybenzaldehyde, myricetin-3-O-rhamnoside, europetin-3-O-rhamnoside, phloretin, myrigalone-G, and myrigalone-B. (see study below)   (5) Myricetin- and europetin-3-O-rhamnoside were identified as major bioactives.
- Screening of crude ethanolic extracts of fruits and leaves for bioactive components yielded alkaloid, tannins, glycosides, formic acid, tartaric acid, flavonoids, and steroid. (see study below) (6)
- Nutritive study per 100 g yielded as follows: total phenolic contents 28.80-30.70 mg/100g, total flavonoids 62.03-62.07 µg/g, antioxidant activity 138.4 - 144.50 µg/g, beta carotene 37.21-37.28g, ascorbic acid (vitamin C) 13.06 to 13.08 mg/100g, moisture 91.70 g%, protein 0.31 g%, fat 0.29 g%, ash 1.24 g%, crude fiber 0.07 g%, calcium 0.64 mg. (11)
- Study of leaves of Syzygium aqueum and S. samarangense yielded two proanthocyanidins, Samarangenins A and B, along with a variety of flavan-3-ols, proanthocyanidins and hydrolyzable and complex tannins. (21)
- In a study of leaves for essential oil, α-Selinene (13.85%), β-caryophyllene (12.72%) and β-selinene were the most abundant constituents in S. aqueum.   (22)
- Study of powdered stem bark isolated two compounds: 2,4-Di-tert-butylphenol & butyrospermol 3-β-O- palmitate. (see study below) (28)
- Chromatographic study isolated 3-O-trans-ferulyl-2a,23-dihydroxyolean-12-en-28-oic acid, betulinic acid, and 3,23-dihydroxy-12-oleanen-28-oic. (see study below) (30)

Properties
- Tambis has been described as lighter and crisp and watery, the Makopa as denser and sometimes with a seed as well. (7)
-
While Malay apple is easily recognized, it may not be easy to distinguish the various water apples and wax jambu fruits.
- Astr
ingence attributed to tannins.
- Studies suggest tyrosinase inhibitory, antioxidant, hypotriglyceridemic, hepatoprotective, anti-inflammatory, analgesic, xanthine oxidase inhibitory, antiangiogenic, antihyperglycemic, adipogenesis enhancing, anticancer, antimicrobial properties

Parts used
Fruit, roots, leaves.

Uses

Edibility
- Fruit is edible, mildly sweet taste similar to apples, and a crisp watery texture.
- Unripe green fruits are eaten raw and used to make pickles, jelly, syrup, and sauces. (11)
- In Malaysia and Indonesia, fruits are used as fruit salad ingredients. (11)
- Leaves are edible, eaten raw or dried. Also, used to wrap food.
- In Malaysia, water apple salad is ceremonially served after childbirth. In Indonesia water apple and wax jambu are used in fruit salads (rujak), and preserved by pickling (asinan).
Folkloric
- Fresh leaves eaten raw as treatment for malaria and pneumonia. (12)
- Infusion of leaves used to treat stomach aches and dysentery. (12)
- In Malaysia, powdered dried leaves used to treat cracked tongue. Roots used to relieve itching and to reduce swelling (15)
Others
- Wood: Wood is heavy, moderately hard, moderately resistant to fungi and termites. Used tor making ordinary tools, tool handles, musical instruments, heavy carpentry, flooring, joinery, etc. (11)

Studies
Tyrosinase Inhibitory Activity / Antioxidant / Leaves:
Study of leaf extracts of S. aqueum showed excellent radical scavenging activity with EC50 of 133 µg/mL DPPH, 65 µg/mL ABTS, and 71 µg/mL Galvinoxyl, with low prooxidant capabilities and a phenolic content of 585-670 mg GAE g/extract. It also exhibited substantial tyrosinase inhibition activity with IC50 of about 60 µg/mL. It showed anti-cellulite activity with 98% activation of lipolysis of adipocytes (fat cells). It was not cytotoxic to Vero cell lines up to 600 µg/mL. The cosmeceutical properties suggest potential for applications in the cosmetic industry.    (3)
Hepatoprotective / Analgesic / Anti-Inflammatory / Leaves: Study of polyphenol-rich extract of leaves showed a plethora of substantial phamacological properties. Extract showed antioxidant properties in-vitro and protected human keratinocytes (HaCaT cells) against UVA damage. It reduced elevated AST, ALT, total bilirubin, TC, and TG in rats with acute CCl4 (carbon tetrachloride) intoxication. It reduced high MDA level, restored GSH and SOD to normal control levels. It exhibited promising anti-inflammatory properties in-vitro with inhibition of LOX, COX-1, and COX-2 with higher COX-2 selectivity than indomethacin and diclofenac. The extract also reduced leukocyte numbers in rats challenged with carrageenan. Results suggest good protection against oxidative stress and free radicals, and a potential for treating oxidative stress related diseases. (4)
Antidiabetic / Antioxidant / Leaves: Study revealed the effectiveness of Syzygium aqueum leaf extract in inhibiting the carbohydrate hydrolyzing enzymes, α- glucosidase and α-amylase at more significant levels than commercial drug acarbose. The extract also inhibited the key enzyme in the polyol pathway, aldose reductase and prevented AGE formation. Unlike TZDs, it did not induce obesity or other side effects. Sub-acute toxicity studies in Sprague-Dawley rats showed no toxicity up to 2000 mg/kg. (see constituents above) (5)(14)
Antimicrobial / Fruits and Leaves: Syzygium aqueum has three varieties: red, green, and white. Study compared the three varieties in its antimicrobial activity and the presence of secondary metabolites. Crude ethanolic extracts of fruits and leaves showed effective antibacterial activity against S. aureus, B. subtilis, E. coli and P. aeruginosa. No inhibition was observed against Aspergillus flavus and Saccharomyces cerevisiae. (see constituents above) (6)
Antioxidant / Fruits: Study compared the antioxidant activity of fruit of water apple and fragrant mango against DPPH as free radical. Vitamin C content of water apple and mango fruit was 0.087% (w/w) and 0.050% (w/w), respectively. Inhibitory concentration 50% values was 4.857µg/ml and 4.379 µg/ml, respectively. Results showed antioxidant activity of water apple was higher than fragrant mango fruit. (9)
Flavanone / Antioxidant / Xanthine Oxidase Inhibitor / Leaves: Study of a methanolic extract of S. aqueum leaves isolated an active compound, demothoxymatteucinol (5,7-dihydroxy-6,8-dimethlyl- flavanone). Results showed mild antioxidant and XO inhibitory activities. At 100 and 50 µg/mL, it could inhibit 25.13% of xanthine oxidase (XO) activity and scavenge 11.87% of DPPH, respectively. (10)
In-Vivo Toxicity Study / Leaves: Study evaluated acute and subchronic toxicity effects of a leaf extract of Syzygium equeum in male Sprague Dawley rat. The extract did not show any signs of toxicity or mortality. Results showed safety with LD50 greater than 2000 mg/kbw. The extract was standardized against myricitrin. (13)
Antioxidant / Potential Antihyperglycemic / Leaves: Study evaluated the antioxidant activity of fresh and dried plant extracts of Paederia foetida and Syzygium aqueum using ß-carotene bleaching and ABTS radical cation assay. Percentage antioxidant activity of all extracts using both assay was between 58 and 80%. Fresh plant samples had higher antioxidant activity than dried samples. (15)
Antiangiogenic / Leaves: Angiogenesis plays a major role in the spread of several pathological processes such as ocular diseases and tumor metastasis. Study evaluated the anti-angiogenic activity of an ethanol extract of S. aqueum leaves using Chorioallantoic Membrane (CAM) assay. Results showed anti-angiogenic activity in CAM measures of mean length density, mean number of junctions, mean number of tubules and mean vascular density. (19)
Anticonvulsant / Anxiolytic / Toxicity Study / Leaves: Study evaluated the anticonvulsant and anxiolytic activity of extract of S. equeum leaves. Oral toxicity study of methanol extract using OECD-423 guidelines showed not mortality or acute toxicity up to 2000 mg/kbw. Study showed anxiolytic activity in mice by Elevated Plus Maze, Rotarod and Open Field methods. Anticonvulsant activity was exhibited by dose dependent protection in MES and PTZ induced convulsion models, with increased seizure latency and reduced seizure duration. (20)
Enhancement of Adipogenesis / Antidiabetic Potential / Leaves: Study investigated the insulin-like and/or insulin-sensitizing effects of S. aqueum leaf extract and its six bioactive compounds 4-hydroxy-benzaldehyde, myricetin-3-O-rhamnoside, europetin-3-O-rhamnoside, phloretin, myrigalone-G and myrigalone-B  in 3T3-L1 adipocytes. Results showed effective enhancement of adipogenesis stimulation of glucose uptake and increase adiponectin secretion in 3T3-L1 adipocytes. The compounds myricetin-3O-rhamnoside and europetin-3-O-rhamnoside showed insulin-like and insulin-sensitizing effects on adipocytes at concentration of 0.08 µM. These compounds were far better than rosiglitazone and other compounds in enhancing adipognesis, stimulating 2-NBDG uptake, and increasing adiponectin secretion. (23)
Tyrosinase Inhibitor in Food Products / Leaves: In this study, response surface methodology (RSM) in combination with central composite rotatable design (CCRD) were performed to optimize the extraction parameters for total phenolic content (TPC) on Syzygium aqueum (S. aqueum) leaves. The effect of operational conditions on the extraction of S. aqueum leaves using carbon dioxide (CO2) on TPC was investigated. 2-propen-1-one,1-(2,4-Dihydroxyphenyl)-3-(4methoxyphenyl)- has similar chemical properties with kaempferol as tyrosinase inhibitor. (24)
Anticancer / Stem Bark: Study of stem bark of Syzygium aqueum isolated oleanolic acid and ß-sitosterol. The isolated compounds showed anticancer activity against HeLa (cervical) and T47D (breast) cancer cell lines by MTT assay. Oleanolic assay was more active on T47D cell line, while ß-sitosterol was more active of HeLa cell line. (25)
Anticancer Triterpenoids / Alphitolic Acid and Arjunolic Acid / Stem Bark: Chromatographic separation and purifications isolated two triterpenoids from nonpolar and semipolar extracts of stem barks, and identified as alphitolic acid and arjunolic acid. The two compounds were tested against human cancer cell lines HeLa, T47D, and A549 using calorimetric assay. Both compounds showed more growth inhibition of HeLa and T47D than A549 cancer cells, with highest activity exhibited by arjunolic acid against HeLa cell lines. (26)
Effect on Triglyceride Levels in White Rats Hypertension / Leaves: Study evaluated effect of methanol extract of water apple leaves on triglyceride levels in white rats (Rattus novergicus) hypertension. Results showed the ME can reduce triglyceride in hypertensive white rats. (27)
2,4-Di-tert-butylphenol and Butyrospermol 3-ß-O-palmitate / Stem Bark: Study of powdered stem bark isolated two compounds: 2,4-Di-tert-butylphenol & butyrospermol 3-β-O- palmitate. Bioactivities have been previously reported for 2,4-Di-tert-butylphenol such as moderate toxicity against HeLa and MCF-7, high antioxidant activity, antibacterial activity against P. aeruginosa and S. aureus, prevention of fungal mycelial growth of A. niger, F. oxysporum and P. chrysogenumon. (28)
Suggested Leaf Architecture and Further Taxonomical Analysis: The two species, Syzygium aqueum and Syzygium samarangense are often confused due to morphological similarities. Study sought to delineate the two confusing taxa, comparing selected laminal and venation characters. While similar characters are shared, laminar size, apex, and base shape, areolation and freely ending veinlets (FEVs) were found to be distinct. Author recommends additional taxonomical analysis using molecular techniques and floral morphology studies to contribute to the resolution of taxonomic complexity and controversies. (29)
Antidiabetic: Chromatographic study isolated 3-O-trans-ferulyl-2a,23-dihydroxyolean-12-en-28-oic acid, betulinic acid, and 3,23-dihydroxy-12-oleanen-28-oic. Study showed antidiabetic activity by inhibition of α-glucosidase enzyme with 50% (?) inhibition at 100 g/mL concentration. (30)
Anti-Cholinesterase Activity / Effect on Learning and Memory: Vascular dementia (VaD) is one of the most common types of dementia in the elderly, initiated by chronic cerebral hypoperfusion (CCH). Medicines that restore level of acetylcholine (ACh) neurotransmitter by inhibiting cholinesterase activity have potential for treatment of VaD patient. Study evaluated the anti-cholinesterase activity of three Malaysian plants (Coccoloba uvifera stems, Mimusops elengi leaves, and Syzygium aqueum leaves) methanol extracts for cognitive-enhancing effects invivo using POBCCA rats. All three plants exhibited good anti-cholinesterase (AChE) and butyrylcholinesterase (BuChE) activities ranging from 3.67 to 16.04 and 5.6 to 13.95 µg/mL, respectively. Extracts of S. aqueum at 200 mg/kg improved both short- and long-term recognition memories and improved spatial learning. Results showed good anti-cholinesterase activity in vitro. Only S. aqueum and M. elengi improved learning and memory function in POBCCA rats. (31)

Availability
- Wild-crafted.
- Cultivated

Updated August 2023
May 2020

                                                      PHOTOS / ILLUSTRATIONS
IMAGE SOURCE: Photo / MYrtaceae: Syzygium equeum / Fruiting twig / Copyright © 2012 by P.B. Pelser & J.F. Barcelona (contact: pieter.pelser@canterbury.ac.nz) [ref. DOL42466] / Non-Commercial Use / Phytoimages.siu.edu
OTHER IMAGE SOURCE: Illustration: / File:Syzygium aqueum / click on image to go to soure page / Public Domain / Wikipedia

OTHER IMAGE SOURCE: Photo : Syzygium aqueum / Tatiana Gerus / Creative Commons Attriibution--Share Alike 2.0 Generic /  image modified / click on image of link to go to source page / Wikimedia Commons

Additional Sources and Suggested Readings
(1)
Syzygium aquem / Synonyms / KEW: Plants of the World Online

(2)
Sorting Syzygium names / /Maintained by: Michel H. Porcher / MULTILINGUAL MULTISCRIPT PLANT NAME DATABASE / Copyright © 1995 - 2020 / A Work in Progress. School of Agriculture and Food Systems. Faculty of Land & Food Resources. The University of Melbourne. Australia.
(3)
Standardized extract of Syzygium aqueum: a safe cosmetic ingredient. / Palanisamy UD, Ling LT, Manaharan T, Sivapalan V, Subramaniam T, Helme MH, Masilamani T / Int J Cosmet Sci, June 2011; 33(3): pp 269-275 / DOI: 10.1111/j.1468-2494.2010.00637.
(4)
Syzygium aqueum: A Polyphenol- Rich Leaf Extract Exhibits Antioxidant, Hepatoprotective, Pain-Killing and Anti-inflammatory Activities in Animal Models / Mansour Sobeh, Mona F Mahmoud, Ganna Petruk, Samar Rezq, Mohamed L Ashour, Michael Wink et al / Front Pharmacol., 2018; 9 / DOI: 10.3389/fphar.2018.00566 / PMCID: PMC5996109 / PMID: 29922158
(5)
SYZYGIUM AQUEUM LEAF EXTRACTS FOR POSSIBLE ANTIDIABETIC TREATMENT / UD Palanisamy, T Manaharan / Acta Hortic. 1098: pp 13-22 / DOI: 10.17660/ActaHortic.2015.1098.1
(6)
Efficacy of Three Varieties of Syzygium aqueum (Tambis) as Antimicrobial Agent and its Bioactive Component / Levitah C Mapatac, Natividad R Mamaoag / IAMURE International Journal of Science and Clinical Laboratory, 2014; 5(1)
(7)
Syzygium aqueum / Wikipedia
(8)
Syzygium aqueum / PROSEA
(9)
ANTIOXIDANT ACTIVITY OF WATER APPLE (SYZYGIUM AQUEUM) FRUIT ANDFRAGRANT MANGO (MANGIFERA ODORATA) FRUIT / Nyi Mekar Saptarini, Irma Erika Herawati / Asian Journal of Pharmaceutical and Clinical Research, May 2017; 10(14): pp 54-56 / doi:10.22159/ajpcr.2017.v10s2.19487.
(10)
Isolation of 5,7-Dihydroxy, 6,8-Dimethyl Flavanone from Syzygium aqueum with Its Antioxidant and Xanthine Oxidase Inhibitor Activities / Muhammad Insanu, Zelika Mega Ramadania, Evelyne Nadia Halim, Rika Hartati, Komar Rusian Wirasutisna / Pharmacognosy Research, 2018; 10(1): pp 60-63 / DOI: 10.4103/pr.pr_59_17
(11)
Dietary Benefits of Watery Rose Apple (Syzygium aqueum (Burm.f.) Alston) / Madhuri Shrikant Sonawane / International Archive of Applied Sciences and Technology, Dec 2018; 9(4): pp 126-129
(12)
Syzygium aqueum / Ken Fern, Tropical Plants Database / Useful Tropical Plants
(13)
In vivo toxicity evaluation of a standardized extract of Syzygium aqueum leaf / Thamilvaani Manaharan, Uma Devi Palanisamy et al / Toxicology Reports, 2014; Vol 1: pp 718-725 /
DOI: 10.1016/j.toxrep.2014.09.006
(14)
Flavonoids isolated from Syzygium aqueum leaf extract as potential antihyperglycaemic agents / Thamilvaani Manaharan, David Appleton, Hwee Ming Cheng, Uma Devi Palanisamy / Food Chemistry, 2012; 132(4): pp 1802-1807 / DOI: 10.1016/j.foodchem.2011.11.147
(15)
Antioxidant Activity and Phenolic Content of Paederia foetida and Syzygium aqueum / Hasnah Osman, Afiday A Rahim, Norhafizah M Isa, and Nornaemah M Bakhir / Molecules, 2009; 14(3): pp 970-978 / https://doi.org/10.3390/molecules14030970 
(19)
Anti-ANGIOGENIC activity of Ethanol Extract of Syzygium aqueum (Tambis) leaves via chicken egg Choriollantoic Membrane (CAM) assay. / Gregorio Antonio C. BatillerNiño Vincent D. CaloAce Philip T. TardoEdson Carlos M. DensingJohn Bryan  N. MendozaCharlene Ann Y. QuidlatRhona Mae G. MancoAleza Mae D. DiamlaValerie  S. Goyenechea, Jamie Glor R. Yu / Thesis-Dissertation, June 2018: Medicine / University of Cebu, School of Medicine
(20)
Evaluation of Anticonvulsant and Anxiolytic Activity of Methanolic Extract of Leaves of Syzygium Aqueum (Brum. F) / Geethu Krishna / Masters thesis, Annai J.K.K. Sampoorani Ammal College of Pharmacy, Komarapalayam.
(21)
Tannins and Related Compounds. CXIX. Samarangenins A and B, Novel Proanthocyanidins with Doubly Bonded Structures, from Syzygium samarangens and S. aqueum / Gen-ichiro Nonaka, Yukari Aifo, Kousuke Aritake, Itsuo Nishioka / Chemical and Pharmaceutical Bulletin, 1992; 40(10): pp 2671-2673 / DOI: https://doi.org/10.1248/cpb.40.2671
(22)
Chemical Profiling of the Essential Oils of Syzygium aqueum, Syzygium samarangense and Eugenia uniflora and Their Discrimination Using Chemometric Analysis / Sobeh Mansour; Braun Markus Santhosh; Krstin Sonja; Youssef Fadia S; Ashour Mohamed L; Wink Michael / 10.1002/cbdv.201600089
(23)
Syzygium aqueum leaf extract and its bioactive compounds enhances pre-adipocyte differentiation and 2-NBDG uptake in 3T3-L1 cells / Manaharan, Thamilvaani Ming, Cheng Hwee Palanisamy, Uma D. / Food Chemistry, 2013; 136(2): pp 354-363 / ISSN : 0308-8146 / DOI: 10.1016/j.foodchem.2012.08.056
(24)
Preliminary study in discovering 2-propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(4-methoxyphenyl)- from syzygium aqueum leaves as a tyrosinase inhibitor in food product: experimental and theoretical approach / Zarudin, Nurul Husna and Abdullah, Erna Normaya and Yunus, Kamaruzzaman and Ku Bulat, Ku Halim and Ahmad, Mohammad Norazmi / International Conference on Clean Water, Air and Soil (CLEANWAS 2019), 26th-28th July 2019, Hanoi, Vietnam
(25)
Anticancer Activity Of Isolated Compounds From Syzygium Aqueum Stem Bark / EE Aung, AN Kristanti, NS Aminah, Y Takaya, R Ramadhan, HT Aung / Rasayan Journal of Chemistry, 2021; 14(1): pp 312-318 / ISSN: 0974-1496 / eISSN: 0976-0083 / DOI: 10.31788/RJC.2021.1416106
(26)
Bioactive triterpenoids from Indonesian medicinal plant Syzygium aqueum / Alfinda Novi Kristanti, Ei Ei Aung, Nanik Siti Aminah, Yoshiaki Takaya, Hnin Thanda Aung, Rico Ramadhan / Open Chemistry, 2022; 20(1): pp 204-211 / DOI: 10.1515/chem-2022-0138
(27)
Effectiveness of Methanol Extract of Jambu Air Leaves (Syzygium aqueum) on Serum Blood Triglycerid Levels of White Rats (Rattus novergicus) Hypertension / Megawati, Ummi Hiras Habisukan, Fahmi Armanda / International Education Conference (IEC) 2021; 1(1)
(28)
Isolation of 2,4-Di-tert-butylphenol and Butyrospermol 3-β-O-palmitate from Syzygium aqueum stem bark / Ei Ei Aung, Alfinda Novi Kristanti, Nanik Siti Aminah, Yoshiaki Takaya, Rico Ramadhan /MOJ Ecology & Environmental Sciences, 2020; 5(4): pp 193-197
(29)
Short Communication: Leaf architectural analysis of confusing Syzygium species: Syzygium aqueum (Burm.f.) Alston and Syzygium samarangense (Blume) Merr. & L.M.Perry (Myrtaceae)
/ Jose Dale L Viacrucis III, Inocencio E Buot Jr / Biodiversitas Journal of Biological Diversity, 2021; 22(6)
(30)
Phytochemicals Constituents in Medicinal Plant Syzygium aqueum (Burm.) Alston (Myrtaceae) / Ei Ei Aung, Alfinda Novi Kristanti, Nanik Siti Aminah, Yoshiaki Takaya, Rico Ramadhan / Egyptian Journal of Chemistry, 2023;p 66(3): pp 301-308
(31)
In vitro anti-cholinesterase activity and in vivo screening of Coccoloba uvifera, Mimusops elengi and Syzygium aqueum extracts on learning and memory function of chronic cerebral hypoperfusion rat / Kesevan Rajah Kumaran, Habibah Abdul Wahab, Zurina Hassan / Neuroscience Research Notes, 2021; 4(2) / DOI: 10.31117/neuroscirn.v4i2.71













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