Family • Annonaceae
Polyalthia suberosa (Roxb.) Thwaites.
CORKY DEBBAR TREE
|Scientific names||Common names|
|Polyalthia suberosa (Roxb.) Thwaites.||Baling-manok (Tag.)|
|Uvaria suberosa Roxb.||Duhat-duhatan (Tag.,)|
|Corky debbar tree (Engl.)|
|Lanutan is a common name shared by: (1) Kalai, Alphonsea arborea (2) Malaatis, Dasymaschalon clusiflorum (3) Kalimatas, Phaenthus ebracteolatus, and (4) Duhat-matsing, Polyalthia suberosa.|
|Polyalthia suberosa (Roxb.) Thwaites is an accepted name. The Plant List|
|Other vernacular names|
|BANGLADESH: Jam debharu, Ham jam.|
|CHINESE: Mei wei mu, Shin guan yin, Lao ren pi, Ji zhao shu, An luo.|
|INDIA: Gua koli, Dudduga chettu.|
|THAI: Klueng klom.|
Fresh roots, bark.
- Ripe fruits are edible.
- Decoction of fresh roots used as abortifacient.
- In Bangladesh, bark used as febrifuge analgesic, and laxative.
- In the tropics, latex used as crude filling for tooth cavities. (8)
- In Andhra Pradesh, India, decoction of grounded root bark mixed with fruits of Piper longum used for puerperal fever. (12)
• Furans / Antiviral Activity: 2-substituted furans from Polyalthia suberosa: Two new 2-substituted furans, 1-(2-furyl)pentacosa16,18-diyne and 23-(2-furyl)tricosa-5,7-diynoic acid, were isolated from the stems of P. suberosa. These compounds, with kalasinamide, N-trans-feruloyltyramine and N-trans-coumaroyltyramine showed anti-HIV activities. (2)
• Anti-HIV Activity: Anti-AIDS Agents, 9. Suberosol, a New C31 Lanostane-Type Triterpene and Anti-HIV Principle from Polyalthia suberosa: In the course of searching for anti-HIV agents, a new triterpene, suberosol, was isolated and studied for anti-HIV activity. Results showed anti-HIV replication activity in H9 lymphocytes cell in vitro. (Publ.1993) (3)
• Cytotoxic: Study isolated four new styryl-lactones, crassalactones A-D together with seven known compounds from an extract of leaves and twigs of PC. Cytotoxic evaluation against mammalian cancer lines were done on all the new isolates. (4)
• Natural Excipient: Study showed the extracted mucilage from the leaves of Polyalthia suberosa is non-toxic, with a potential as a suspending agent, binding agent and pharmaceutical adjuvant. (6)
• Antibacterial / Analgesic / Antidiarrheal / Cytotoxic / Leaves: A methanol extract of leaves showed moderate antibacterial activity against Vibrio cholerae, Shigella sonei, Staphylococcus aureus, Staphylococcus epidermis, and Streptococcus saprophyticus. It produces significant inhibition in acetic induced writhing in mice comparable to diclofenac. It showed an antidiarrheal effect on castor oil-induced diarrhea in mice. Also, it exhibited high level of cytotoxicity in brine shrimp lethality bioassay. (8)
• Nutrient Analysis: Fruits yield a protein content of 1.9% . Micronutrient analysis yielded per mg/100g: iron 4.19, sodium 25.09, potassium 845.76, calcium 62.72, copper 1.33, manganese 5.35, zinc 2.25. (9)
• Mucilage / Non-Toxic / Leaves: Study results extracted mucilage from leaves of Polyalthia suberosa (PMS) is non toxic, has the potential as a suspending agent, as binding agent and as pharmaceutical adjuvant. (11)
• Antioxidant / Analgesic / Antidiarrheal / Bark and Fruits: Study screened hydromethanol extracts of leaves, bark and fruits of Polyalthia suberosa for antioxidant, analgesic, and antidiarrheal activity. Bark extracts showed maximum reducing activity, higher than standard reference ascorbic acid. All parts showed analgesic activity with significant (p<0.05-0.01) inhibition of writhing reaction in a dose-dependent manner. In castor oil-induced diarrhea, there was statistically significant (p<0.05) inhibition of frequency of diarrhea, the bark showing 69.52% inhibition wile the fruits showed 63.81% inhibition at 400 mg/kg dose level. Overall, bark and fruit extracts showed strong antioxidant potential with excellent analgesic and antidiarrheal activity. (13)
• Analgesic / CNS Depressant / Bark and Leaves: Study of crude hydromethanolic extracts of bark and leaves showed remarkable cytotoxic, CNS depressant (open field and hole cross tests) and analgesic (acetic acid-induced writhing test for visceral pain and tail immersion tests for central activity) potential. The extract inhibited both mechanisms of pain suggesting potential as a narcotic analgesic. Alkaloids, flavonoids, tannin, saponin, carbohydrates and steroids present may be responsible for the observed effects. (14)
Last Update January 2017
|IMAGE SOURCE: Photograph / Polyalthia suberosa (Roxb.) Benth. & Hook.f. / © Digital Flora of Karnataka Digital Flora of Karnataka by Herbarium JCB is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. / click on image to go to source page / Herbarium JCB|
|IMAGE SOURCE: Illustration / Polyalthia suberosa (Roxb.) Thw. / Collected by www.plant.ac.cn / Click on image to go to source page / Zhiwutong|
Sources and Suggested Readings
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